Results 61 to 70 of about 55,201 (251)

A Randomized, Double-Blind, Placebo-Controlled, Crossover, Dose-Ranging Multicenter Study to Determine the Effect of Sublingual Nitroglycerin Spray on Exercise Capacity in Patients with Chronic Stable Angina

Clinical Medicine Insights: Cardiology, 2012
Background Sublingual nitroglycerin increases exercise duration in patients with stable angina. Brief results from this study were published previously in German.
Udho Thadani, Thomas Wittig
doaj   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Relationship between high-sensitivity C-reactive protein serum levels and the severity of coronary artery stenosis in patients with coronary artery disease

ARYA Atherosclerosis, 2016
BACKGROUND: High-sensitivity C-reactive protein (hs-CRP) inflammatory biomarker is one of the best informative markers of prognosis of coronary artery disease (CAD) that has been studied.
Seyed Masoud Seyedian, Farzaneh Ahmadi, Razieh Dabagh, Hannaneh Davoodzadeh   +3 more
doaj  

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Comparison of functional exercise capacity, quality of life and respiratory and peripheral muscle strength between patients with stable angina and healthy controls

Journal of International Medical Research, 2020
Objective We aimed to compare functional exercise capacity, respiratory and peripheral muscle strength, pulmonary function and quality of life between patients with stable angina and healthy controls.
Irem Huzmeli, Aysel-Yildiz Ozer, Oguz Akkus, Nihan Katayıfcı, Fatih Sen, Saadet Ufuk Yurdalan, Mine Gulden Polat   +6 more
doaj   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

CLINICAL FEATURES OF MANIFESTATIONS OF MYOCARDIAL ISCHEMIA IN PATIENTS WITH STABLE ANGINA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Кубанский научный медицинский вестник, 2017
Aim.To evaluate the comparative frequency of various manifestations of myocardial ischemia depending on chronic obstructive pulmonary disease (COPD), its severity and pulmonary hyperinflation (PHI) in patients with stable effort angina having indications
V. K. ZAFIRAKI, E. D. KOSMACHEVA
doaj   +1 more source

Lower Risk of Cardiovascular Events in Patients With Clinical Atherosclerotic Cardiovascular Disease Who Initiated Semaglutide 2.4 mg in the Real‐World: Results From the SCORE—Clinical ASCVD Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between semaglutide 2.4 mg and major adverse cardiovascular events (MACE) among adults with clinical atherosclerotic cardiovascular disease (ASCVD) and overweight/obesity without diabetes in real‐world clinical practice.
Michael G. Nanna, Carlos Mena‐Hurtado, Victoria Divino, Zhenxiang Zhao, Yan Chen, Joanna Boland, Jinlin Song, Andrea Traina, Kerem Ozer, Filip K. Knop, Kim G. Smolderen   +10 more
wiley   +1 more source

Serum nonmercaptalbumin to total albumin ratio and bilirubin predict ADL decline in older adults with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
In a longitudinal cohort of older adults with type 2 diabetes, incident ADL disability was evaluated. Higher HNA%, lower serum bilirubin, and older age independently predicted the risk of disability. Their combined assessment may offer clinically useful tools for identifying individuals at elevated risk of functional deterioration.
Yukihiro Inoguchi, Toyoshi Inoguchi, Keiko Yasukawa, Saki Fukuhara, Tomoaki Etoh, Mitsunori Masakado, Mayumi Yamato, Fumio Umeda, Yutaka Yatomi, Teruaki Yamauchi, Masatoshi Nomura   +10 more
wiley   +1 more source

The Determinants of Negotiated Pharmaceutical Prices

The Journal of Industrial Economics, EarlyView.
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert, Sebastian Linde, Brandon Norton   +2 more
wiley   +1 more source