Results 101 to 110 of about 3,027,054 (295)

Asset Pricing with Incomplete Information under Stable Shocks [PDF]

open access: yes
We study a consumption based asset pricing model with incomplete information and alpha-stable shocks. Incomplete information leads to a non-Gaussian filtering problem.
Prasad V. Bidarkota   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Conditional Distributions and Characterizations of Multivariate Stable Distribution

open access: yesJournal of Multivariate Analysis, 1995
Let \(X\) and \(Y\) be two identically distributed random variables. \textit{M. Ahsanullah} [Metrika 32, 215-218 (1985; Zbl 0609.62019)] showed that if the conditional distribution of \(X|Y=y\) is a normal distribution with mean \(ay+b\) and with variance \(\sigma^2\), then \(|a|
openaire   +2 more sources

A parametric bootstrap for heavytailed distributions [PDF]

open access: yes
It is known that Efron's resampling bootstrap of the mean of random variables with common distribution in the domain of attraction of the stable laws with infinite variance is not consistent, in the sense that the limiting distribution of the bootstrap ...
Russell Davidson, Adriana Cornea
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The Degree of Stability of Price Diffusion [PDF]

open access: yes
The distributional form of financial asset returns has important implications for the theoretical and empirical analyses in economics and finance. It is now a well-established fact that financial return distributions are empirically nonstationary, both ...
Cornelis A. Los
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Machine Learning for Enabling High-Data-Rate Secure Random Communication: SVM as the Optimal Choice over Others

open access: yesMathematics
Machine learning (ML) has become a key ingredient in revolutionizing the physical layer security of next-generation devices across Industry 4.0, healthcare, and communication networks.
Areeb Ahmed, Zoran Bosnić
doaj   +1 more source

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