Results 121 to 130 of about 3,027,054 (295)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Stable distributions in finance markets modeling. [PDF]

open access: yes, 2007
Stable distributions are a rich class of probability distributions that allow skewness and heavy tails. The lack of closed formulas for densities and distribution functions for all distributions (except Gaussian, Cauchy and Levy distributions) is the ...
Šakytė, Edita,
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Monte Carlo-Based Tail Exponent Estimator [PDF]

open access: yes
In this paper we study the finite sample behavior of the Hill estimator under α-stable distributions. Using large Monte Carlo simulations we show that the Hill estimator overestimates the true tail exponent and can hardly be used on samples with small ...
Jozef Barunik, Lukas Vacha
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Nested Archimedean Copulas Meet R: The nacopula Package [PDF]

open access: yes
The package nacopula provides procedures for constructing nested Archimedean copulas in any dimensions and with any kind of nesting structure, generating vectors of random variates from the constructed objects, computing function values and probabilities
Marius Hofert, Martin Maechler
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Fractional flux and non-normal diffusion

open access: yesElectronic Journal of Differential Equations, 2007
Fractional diffusion equations are widely used for mass spreading in heterogeneous media. The correspondence between fractional equations and random walks based upon stable Levy laws, keeps in analogy with that between heat equation and Brownian motion.
Ali Abdennadher, Marie-Christine Neel
doaj  

Using stable distributions to characterize proton pencil beams. [PDF]

open access: yesMed Phys, 2018
Van den Heuvel F   +3 more
europepmc   +1 more source

Strictly stable distributions on convex cones

open access: yes, 2008
Using the LePage representation, a symmetric alpha-stable random element in Banach space B with alpha from (0,2) can be represented as a sum of points of a Poisson process in B. This point process is union-stable, i.e.
Davydov, T.   +5 more
core  

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