Results 121 to 130 of about 3,027,054 (295)
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Stable distributions in finance markets modeling. [PDF]
Stable distributions are a rich class of probability distributions that allow skewness and heavy tails. The lack of closed formulas for densities and distribution functions for all distributions (except Gaussian, Cauchy and Levy distributions) is the ...
Šakytė, Edita,
core +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Monte Carlo-Based Tail Exponent Estimator [PDF]
In this paper we study the finite sample behavior of the Hill estimator under α-stable distributions. Using large Monte Carlo simulations we show that the Hill estimator overestimates the true tail exponent and can hardly be used on samples with small ...
Jozef Barunik, Lukas Vacha
core
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Nested Archimedean Copulas Meet R: The nacopula Package [PDF]
The package nacopula provides procedures for constructing nested Archimedean copulas in any dimensions and with any kind of nesting structure, generating vectors of random variates from the constructed objects, computing function values and probabilities
Marius Hofert, Martin Maechler
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Fractional flux and non-normal diffusion
Fractional diffusion equations are widely used for mass spreading in heterogeneous media. The correspondence between fractional equations and random walks based upon stable Levy laws, keeps in analogy with that between heat equation and Brownian motion.
Ali Abdennadher, Marie-Christine Neel
doaj
Using stable distributions to characterize proton pencil beams. [PDF]
Van den Heuvel F +3 more
europepmc +1 more source
Strictly stable distributions on convex cones
Using the LePage representation, a symmetric alpha-stable random element in Banach space B with alpha from (0,2) can be represented as a sum of points of a Poisson process in B. This point process is union-stable, i.e.
Davydov, T. +5 more
core

