Results 71 to 80 of about 3,027,054 (295)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Portuguese stock market: A long-memory process?
This paper gives a basic overview of the various attempts at modelling stochastic processes for stock markets with a specific application to the Portuguese stock market data.
Sameer Rege, Samuel Gil Martín
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Indirect estimation of elliptical stable distributions [PDF]
We present an indirect estimation approach for elliptical stable distributions which relies on the use of a multivariate t distribution as auxiliary model.
LOMBARDI, Marco, VEREDAS, David
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Models for Heavy-tailed Asset Returns [PDF]
Many of the concepts in theoretical and empirical finance developed over the past decades – including the classical portfolio theory, the Black-Scholes-Merton option pricing model or the RiskMetrics variance-covariance approach to VaR – rest upon the ...
Weron, Rafal +2 more
core +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Measuring distributed durations with stable errors
The round-trip duration measurement technique is fundamental in solving many problems in asynchronous distributed systems. In essence, this technique provides the means for reading remote clocks with a known and bounded error. Therefore, it is used as a fundamental building block in several clock synchronization algorithms.
António Casimiro +3 more
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Multifractal Nature of Diesel Engine Rattle Noise in Vehicle
The investigation results of the emission of noises accompanying the diesel engine powertrain running in unloaded condition at low or idle speed, are presented in the hereby paper.
Andrzej PUCHALSKI, Iwona KOMORSKA
doaj +1 more source

