Results 61 to 70 of about 376,571 (281)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Coupled folding-binding versus docking: A lattice model study

, 2003
Using a simple hydrophobic/polar protein model, we perform a Monte Carlo study of the thermodynamics and kinetics of binding to a target structure for two closely related sequences, one of which has a unique folded state while the other is unstructured ...
Gupta, Nitin, Irbäck, Anders
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

First Report of Mermithidae (Enoplea: Mermithida) Parasitizing Adult Stable Flies in Japan

Journal of Nematology
Mermithidae is a family of nematodes that parasitize a wide range of invertebrates worldwide. Herein, we report nematodes that were unexpectedly found in three of 486 adult stable flies (Stomoxys calcitrans) captured from three farms (F1, F2, and F3) in ...
Shimizu Kaori, Saito Taizo, Takashima Yasuhiro, Okada Haruhiko, Asakawa Mitsuhiko, Inoshima Yasuo   +5 more
doaj   +1 more source

Effects of Different Amendment Materials on Reclaimed Soil Structure and Organic Matter Content of Hollow Village in Loess Region

Shuitu baochi tongbao, 2022
[Objective] The poor structure and low fertility of reclaimed soil of abandoned homesteads in hollow villages in the loess area were addressed in order to provide a theoretical basis for improving the quality of reclaimed soils.
Liu Zhe, Wang Huanyuan, Sun Yingying, Sun Zenghui, Zhang Ruiqing   +4 more
doaj   +1 more source

A review and illustrated description of Musca Crassirostris, one of the most neglected livestock hematophageous flies [PDF]

, 2019
Tabanids, stomoxyine flies, hippoboscids and tsetse flies are the most well‐known brachyceran biting flies of livestock. Only a few other higher Diptera have developed the unique mouthparts required for blood feeding.
Al‐Saffar H., Borror D., Chin H., Desquesnes M., Dorrah M.A., Du Toit R., Gill B., Gooding R.H., Hafez M., Huang Y.‐T., Huckett H., James M., Kigaye M.K., Laveissiere C., M. Desquesnes, Moradi S., Nevill E., Nevill E., Nihei S., P. Chalermwong, Patton W., Patton W.S., Patton W.S., Patton W.S., R. Masmeatathip, S. Jittapalapong, S. Onju, Skidmore P., Taylor M.A., Tumrasvin W., Tyagi B.K., Van Emden F.I., Veer V., Walker A., West L.S., Yatham N.R.   +35 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Data Provenance Inference in Logic Programming: Reducing Effort of Instance-driven Debugging [PDF]

, 2013
Data provenance allows scientists in different domains validating their models and algorithms to find out anomalies and unexpected behaviors. In previous works, we described on-the-fly interpretation of (Python) scripts to build workflow provenance graph
Huq, Mohammad Rezwanul, Mileo, Alessandra, Wombacher, Andreas   +2 more
core   +2 more sources

Efficient Emptiness Check for Timed B\"uchi Automata (Extended version) [PDF]

, 2010
The B\"uchi non-emptiness problem for timed automata refers to deciding if a given automaton has an infinite non-Zeno run satisfying the B\"uchi accepting condition. The standard solution to this problem involves adding an auxiliary clock to take care of
B Berthomieu, B Bérard, B. Srivathsan, C Daws, DL Dill, F Herbreteau, F Herbreteau, Frédéric Herbreteau, G Behrmann, G Behrmann, G Li, H Bowman, Igor Walukiewicz, J-M Couvreur, J-M Couvreur, JJ Jessen, K Havelund, M Bozga, P Bouyer, P Bouyer, R Alur, R Alur, R Gómez, S Schwoon, S Tripakis, S Tripakis   +25 more
core   +6 more sources