Results 101 to 110 of about 2,400,643 (255)

Isotopic Analysis (δ¹³C, δ¹⁵N, and δ³⁴S) of Modern Terrestrial, Marine, and Freshwater Ecosystems in Greece: Filling the Knowledge Gap for Better Understanding of Sulfur Isotope Imprints—Providing Insights for the Paleo Diet, Paleomobility, and Paleoecology Reconstructions

Applied Sciences
This study provides a comprehensive database of sulfur isotope values from Greece, including samples of C3 and C4 plants and terrestrial and aquatic animal bones.
Petros Karalis, Elissavet Dotsika, Anastasia-Electra Poutouki, Giorgos Diamantopoulos, Liana Gkelou, Dafni Kyropoulou, Spyridon Bellas, Platon N. Gamaletsos   +7 more
doaj   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

Variation in the carbon and nitrogen isotopic signatures of pig remains from prehistoric sites in the Near East and Central Europe [PDF]

, 2013
The first results of carbon and nitrogen (δ13C, δ15N) stable isotope analyses of domestic pig (Sus domesticus Erxl., 1777) remains from three prehistoric sites are presented.
Bartosiewicz, Laszlo, Pickard, Catriona, Bonsall, Clive, Schoop, Ulf-Dietrich, Vaughan, Maureen   +4 more
core  

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

Advanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu, Chelsea N. Brown, Zeki Duman, Rose Mery Bakestani, Carl M. Kirkpatrick, Joao Hespanha, Tod Kippin, Kevin W. Plaxco   +7 more
wiley   +1 more source

Fluctuations in Medium Viscosity May Affect the Stability of the CAG Tract in the ATXN2 Gene

Biomedicines
Background: Trinucleotide repeats are the cause of many neurodegenerative diseases that are currently incurable. In this regard, the question of the causes of occurrence and methods of prevention or treatment of diseases caused by the expansion of ...
Anna Dorohova, Oksana Lyasota, Stepan Dzhimak, Alexandr Svidlov, Olga Leontyeva, Mikhail Drobotenko   +5 more
doaj   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Differences in the isotopic composition of individual grains and aggregated seed samples affect interpretation of ancient plant cultivation practices

Frontiers in Environmental Archaeology
The stable carbon (δ13C) and nitrogen (δ15N) isotope analysis of charred archaeological grains provides a remarkably precise scale of information: the growing conditions under which a plant was cultivated in a single field and season. Here we investigate
Nathaniel James, Nathaniel James, Christine Winter-Schuh, Christine Winter-Schuh, J. Mark Kenoyer, Jade D'Alpoim Guedes, Cheryl A. Makarewicz, Cheryl A. Makarewicz, Cheryl A. Makarewicz   +8 more
doaj   +1 more source

¹⁵N stable isotope probing of pulp and paper wastewaters [PDF]

, 2008
Stable isotope probing (SIP) is an established technique that can be applied to identify the metabolically active micro-organisms within a microbial population.
Addison, Sarah Louise
core  

Influence of production variables and starting material on charcoal stable isotopic and molecular characteristics [PDF]

, 2008
We present a systematic study on the effect of starting species, gas composition, temperature, particle size and duration of heating upon the molecular and stable isotope composition of high density (mangrove) and low density (pine) wood.
Snape, C.E., Bird, M.I., Apperley, D., Ascough, P.L., Wormald, Philip, Wormald, P., Apperley, David   +6 more
core   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source