Results 51 to 60 of about 375,375 (306)

Isotopes in hydrology and hydrogeology [PDF]

open access: yes, 2019
The structure, status, and processes of the groundwater system, which can only be acquired through scientific research efforts, are critical aspects of water resource management. Isotope hydrology and hydrogeology is a genuinely interdisciplinary science.
Barbieri, Maurizio
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Testing a dual isotope model to track carbon and water gas exchanges in a Mediterranean forest

open access: yesiForest - Biogeosciences and Forestry, 2009
Due to climate change, drier summers have been observed over the last ten years in Mediterranean areas. Increasing drought levels may have a different weight in influencing the stomatal versus photosynthetic activity of forests, altering the water-use ...
Ripullone F   +6 more
doaj   +1 more source

Syntheses of Stable Isotope [13C]/D Labelled p-Methoxybenzoic Acid

open access: yesJournal of Isotopes, 2020
Stable isotope labelled p-methoxybenzoic acid is an important intermediate in the synthesis of stable isotope labelled preservative, anti-microbial, anti-fungal, spices, and other internal standard reagentsspices, drugs and other compounds.
WANG Wei;DU Xiaoning;XU Jianfei;LEI Wen
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Controls on methane concentration and stable isotope (δ2H-CH4 and δ13C-CH4) distributions in the water columns of the Black Sea and Cariaco Basin [PDF]

open access: yes, 2006
Methane (CH4) concentration and stable isotope (δ2H-CH4 and δ13C-CH4) depth distributions show large differences in the water columns of the Earth's largest CH4-containing anoxic basins, the Black Sea and Cariaco Basin.
Albert   +69 more
core   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Labrador Sea freshening at 8.5 ka BP caused by Hudson Bay Ice Saddle collapse

open access: yesNature Communications, 2019
The exact freshwater scenario that caused the 8.2 ka cold event is still debated. This study presents new evidence for a severe Labrador shelfwater freshening 8500 years ago that was caused by the Hudson Bay Ice Saddle collapse following a warming in ...
Annalena Antonia Lochte   +6 more
doaj   +1 more source

Synthesis of Stable Isotope Deuterium Labeled Levofloxacin-D3

open access: yesJournal of Isotopes, 2023
In order to improve the stable isotope utilization rate, a simple and inexpensive synthesis method was developed. The synthesis of levofloxacin is based on piperazine as the starting material, and the reaction with carbobenzoxy chloride (CBZ-Cl) to get ...
XU Zhong jie;ZHANG Li;SUN Wen;ZHANG Pengshuai;LEI Wen
doaj   +1 more source

Links between central Greenland stable isotopes, blocking and extreme climate variability over Europe at decadal to multidecadal time scales [PDF]

open access: yes, 2016
The link between central Greenland stable oxygen isotopes, atmospheric blocking frequency and cold temperature extremes at decadal to multidecadal time scales is investigated using observed and proxy data as well as model experiments.
Ionita, Monica   +3 more
core   +1 more source

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