Results 11 to 20 of about 2,139,344 (304)

Historical and contemporary stable isotope tracer approaches to studying mammalian protein metabolism. [PDF]

open access: yesMass Spectrom Rev, 2018
Over a century ago, Frederick Soddy provided the first evidence for the existence of isotopes; elements that occupy the same position in the periodic table are essentially chemically identical but differ in mass due to a different number of neutrons ...
Wilkinson DJ.
europepmc   +2 more sources

Physiologic requirement for iron in pregnant women, assessed using the stable isotope tracer technique [PDF]

open access: yesNutrition & Metabolism, 2020
Background Knowledge of the physiologic requirement for iron, the core index for the formulation of a dietary reference intake (DRI), is of great importance for the health of a pregnant woman and her fetus, and can help a mother accurately plan her iron ...
Jie Cai   +12 more
doaj   +2 more sources

A novel stable isotope tracer method to simultaneously quantify skeletal muscle protein synthesis and breakdown [PDF]

open access: yesMetabolism Open, 2020
Background/aims: Methodological challenges have been associated with the dynamic measurement of muscle protein breakdown (MPB), as have the measurement of both muscle protein synthesis (MPS) and MPB within the same experiment.
Hannah Crossland   +3 more
doaj   +2 more sources

AccuCor2: isotope natural abundance correction for dual-isotope tracer experiments [PDF]

open access: yesLaboratory Investigation, 2021
Stable isotope labeling techniques have been widely applied in the field of metabolomics and proteomics. Before the measured mass spectral data can be used for quantitative analysis, it must be accurately corrected for isotope natural abundance and ...
Yujue Wang   +2 more
semanticscholar   +2 more sources

Response of Summer Maize Photosynthate Accumulation and Distribution to Shading Stress Assessed by Using 13CO2 Stable Isotope Tracer in the Field. [PDF]

open access: yesFront Plant Sci, 2017
Maize is one of the most important crops globally that provides food, feed, and bioenergy. However, shading stress threatens maize production. In this study, we investigated the effects of shading on photosynthate accumulation and distribution of summer ...
Gao J   +5 more
europepmc   +2 more sources

Positional Enrichment by Proton Analysis (PEPA): A One-Dimensional 1H-NMR Approach for 13C Stable Isotope Tracer Studies in Metabolomics

open access: yesAngewandte Chemie - International Edition, 2017
A novel metabolomics approach for NMR‐based stable isotope tracer studies called PEPA is presented, and its performance validated using human cancer cells.
Miguel A Rodríguez   +2 more
exaly   +2 more sources

Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR

open access: yesScientific Reports, 2018
Experiments with stable isotope tracers such as 13C and 15N are increasingly used to gain insights into metabolism. However, mass spectrometric measurements of stable isotope labeling experiments should be corrected for the presence of naturally ...
Katja Dettmer   +2 more
exaly   +2 more sources

Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans

open access: yesNutrition & Metabolism, 2011
Background Minimizing the number of muscle biopsies has important methodological implications and minimizes subject discomfort during a stable isotope amino acid infusion.
Baker Steven K   +5 more
doaj   +2 more sources

Stable Isotope–Assisted Plant Metabolomics: Combination of Global and Tracer-Based Labeling for Enhanced Untargeted Profiling and Compound Annotation

open access: yesFrontiers in Plant Science, 2019
Untargeted approaches and thus biological interpretation of metabolomics results are still hampered by the reliable assignment of the global metabolome as well as classification and (putative) identification of metabolites.
Maria Doppler   +10 more
doaj   +2 more sources

Stable and radiogenic isotopes as tracers for soil degradation [PDF]

open access: yes, 2008
Soil erosion seriously threatens mountain slopes. Direct measurement of soil erosion in the field is difficult and needs long term recording. However, stable and radiogenic isotopes are potential tracers for soil erosion estimation and would enable a quick and easy estimation of soil erosion. Soil degradation of upland soils influences nutrient content
Schaub, Monika
openaire   +3 more sources

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