Results 71 to 80 of about 3,566,207 (291)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
THE ISSUES OF STABLE ECONOMIC PROCESSES DEVELOPMENT
Russian Journal of Economics and Law, 2007 The article views the issues of analysis, estimation, predicting and planning of stable economic processes in the market environment. The author justifies the necessity to join the leading enterprises with the science of economics in order to review the ...
R. N. Akhmetzyanov
doaj
Persistence of integrated stable processes [PDF]
, 2014 We compute the persistence exponent of the integral of a stable L\'evy process in terms of its self-similarity and positivity parameters. This solves a problem raised by Z. Shi (2003).
Profeta, Christophe, Simon, Thomas
core +1 more source
Spatial risk measures and applications to max-stable processes
, 2016 The risk of extreme environmental events is of great importance for both the authorities and the insurance industry. This paper concerns risk measures in a spatial setting, in order to introduce the spatial features of damages stemming from environmental
Koch, Erwan
core +1 more source
Stochastic Processes and their Applications, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
MathematicsA common approach to simulating a Lévy process is to truncate its shot-noise representation. We focus on subordinators and introduce the remainder process, which represents the jumps that are removed by the truncation.
Michael Grabchak
doaj +1 more source
Journal of Advances in Modeling Earth Systems, 2023 With the recent advances in data science, machine learning has been increasingly applied to convection and cloud parameterizations in global climate models (GCMs). This study extends the work of Han et al. (2020, https://doi.org/10.1029/2020MS002076) and
Yilun Han, Guang J. Zhang, Yong Wang
doaj +1 more source