Results 91 to 100 of about 1,239,268 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
On the Structure of Stationary Stable Processes
The principal result of the paper is a unique in distribution decomposition of stationary symmetric non-Gaussian stable processes \(\{X_t, t \to T\}\) (with \(T = \mathbb{R}\) or \(T = \mathbb{Z})\) into three independent parts \(X =_d X^{(1)} + X^{(2)} + X^{(3)}\).
openaire +2 more sources
"Bayesian Estimation and Particle Filter for Max-Stable Processes" [PDF]
Extreme values are often correlated over time, for example, in a financial time series, and these values carry various risks. Max-stable processes such as maxima of moving maxima (M3) processes have been recently considered in the literature to describe ...
Zhengjun Zhang +2 more
core
Stable and radiogenic isotopes as tracers for soil degradation [PDF]
Soil erosion seriously threatens mountain slopes. Direct measurement of soil erosion in the field is difficult and needs long term recording. However, stable and radiogenic isotopes are potential tracers for soil erosion estimation and would enable a ...
Schaub, Monika
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Lamperti transformation for self-similar processes [PDF]
In this paper we establish the uniqueness of the Lamperti transformation leading from self-similar to stationary processes, and conversely. We discuss alpha-stable processes, which allow to understand better the difference between the Gaussian and non ...
Makoto Maejima +2 more
core
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Mean field games based on the stable-like processes
In this paper, we investigate the mean field games with K classes of agents who are weakly coupled via the empirical measure. The underlying dynamics of the representative agents is assumed to be a controlled nonlinear Markov process associated with ...
Troeva, Marianna +2 more
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

