Results 71 to 80 of about 1,239,268 (312)

Series representation of time-stable stochastic processes [PDF]

open access: yes, 2018
A stochastically continuous process ɛ(t), t­ ≥ 0, is said to be time-stable if the sum of n i.i.d. copies of ɛ equals in distribution the time-scaled stochastic process ɛ(nt), t­ ≥ 0. The paper advances the understanding of time-stable processes by means
Molchanov, Ilya   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Max-stable processes and stationary systems of Levy particles

open access: yes, 2015
We study stationary max-stable processes {n(t): t is an element of R} admitting a representation of the form n(t) = max(i is an element of N) (U-i +Y-i(t)), where Sigma(infinity)(i=1) delta U-i is a Poisson point process on R with intensity e(-u)du, and ...
Engelke, Sebastian   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

THE ISSUES OF STABLE ECONOMIC PROCESSES DEVELOPMENT

open access: yesRussian Journal of Economics and Law, 2007
The article views the issues of analysis, estimation, predicting and planning of stable economic processes in the market environment. The author justifies the necessity to join the leading enterprises with the science of economics in order to review the ...
R. N. Akhmetzyanov
doaj  

Spectral asymptotics for stable trees [PDF]

open access: yes, 2010
We calculate the mean and almost-sure leading order behaviour of the high frequency asymptotics of the eigenvalue counting function associated with the natural Dirichlet form on alpha-stable trees, which lead in turn to short-time heat kernel asymptotics
Croydon, David A., Hambly, Ben M.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On the Self-Similarity of Remainder Processes and the Relationship Between Stable and Dickman Distributions

open access: yesMathematics
A common approach to simulating a Lévy process is to truncate its shot-noise representation. We focus on subordinators and introduce the remainder process, which represents the jumps that are removed by the truncation.
Michael Grabchak
doaj   +1 more source

An Ensemble of Neural Networks for Moist Physics Processes, Its Generalizability and Stable Integration

open access: yesJournal of Advances in Modeling Earth Systems, 2023
With the recent advances in data science, machine learning has been increasingly applied to convection and cloud parameterizations in global climate models (GCMs). This study extends the work of Han et al. (2020, https://doi.org/10.1029/2020MS002076) and
Yilun Han, Guang J. Zhang, Yong Wang
doaj   +1 more source

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