Results 51 to 60 of about 354,201 (259)
Permutations Sorted by a Finite and an Infinite Stack in Series [PDF]
, 2018 We prove that the set of permutations sorted by a stack of depth $t \geq 3$ and an infinite stack in series has infinite basis, by constructing an infinite antichain. This answers an open question on identifying the point at which, in a sorting process with two stacks in series, the basis changes from finite to infinite.
Murray Elder, Yoong Kuan Goh
openaire +3 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Nature CommunicationsHomologous recombination (HR) repairs double-stranded DNA breaks (DSBs) by generating single-stranded DNA (ssDNA), which is initially coated by Replication Protein A (Rpa).
Jaigeeth Deveryshetty +13 more
doaj +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
tum-gis/tum-gis-iot-stack-k8s: tum-gis-iot-stack-k8s-0.9.8
, 2023 Helm Chart for the TUM-GI IoT ...
Benedikt Schwab +2 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Poset associahedra and stack-sorting
Discrete MathematicsFor any finite connected poset $P$, Galashin introduced a simple convex $(|P|-2)$-dimensional polytope $\mathscr{A}(P)$ called the poset associahedron. For a certain family of posets, whose poset associahedra interpolate between the classical permutohedron and associahedron, we give a simple combinatorial interpretation of the $h$-vector.
Son Nguyen, Andrew Sack
openaire +2 more sources
Comparing Algorithms for Sorting with t Stacks in Series [PDF]
Annals of Combinatorics, 2004 We show that the left-greedy algorithm is a better algorithm than the right-greedy algorithm for sorting permutations using t stacks in series when t>1. We also supply a method for constructing some permutations that can be sorted by t stacks in series and from this get a lower bound on the number of permutations of length n that are sortable by t ...
openaire +3 more sources
tum-gis/tum-gis-iot-stack-k8s: tum-gis-iot-stack-k8s-0.9.6
, 2023 Helm Chart for the TUM-GI IoT ...
Willenborg, Bruno +2 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source