Results 51 to 60 of about 344,156 (265)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The pop-stack-sorting operator on Tamari lattices
Motivated by the pop-stack-sorting map on the symmetric groups, Defant defined an operator $\mathsf{Pop}_M : M \to M$ for each complete meet-semilattice $M$ by $$\mathsf{Pop}_M(x)=\bigwedge(\{y\in M: y\lessdot x\}\cup \{x\}).$$ This paper concerns the dynamics of $\mathsf{Pop}_{\mathrm{Tam}_n}$, where $\mathrm{Tam}_n$ is the $n$-th Tamari lattice.
openaire +3 more sources
tum-gis/tum-gis-iot-stack-k8s: tum-gis-iot-stack-k8s-0.9.5
Helm Chart for the TUM-GI IoT ...
Benedikt Schwab +2 more
core +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On Multi-stack Visibly Pushdown Languages
We contribute to the theory of formal languages of visibly multistack pushdown automata (MVPA). First, we show closure under the main operations and decidability of the main decision problems for the class of MVPA restricted to computations where a ...
Parlato, Gennaro +2 more
core +1 more source
Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Homologous recombination (HR) repairs double-stranded DNA breaks (DSBs) by generating single-stranded DNA (ssDNA), which is initially coated by Replication Protein A (Rpa).
Jaigeeth Deveryshetty +13 more
doaj +1 more source
Comparing Algorithms for Sorting with t Stacks in Series [PDF]
We show that the left-greedy algorithm is a better algorithm than the right-greedy algorithm for sorting permutations using t stacks in series when t>1. We also supply a method for constructing some permutations that can be sorted by t stacks in series and from this get a lower bound on the number of permutations of length n that are sortable by t ...
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
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openaire +1 more source

