Results 71 to 80 of about 344,156 (265)
IEEE AccessFor decades, real-time digital control systems have enabled countless applications across industry, transportation, defense, and science. A more recent trend is enhancing their interconnections using hardware and protocols, delivering timing performance ...
Gabriele Brugnoni, Ludovico Minati
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Fertility monotonicity and average complexity of the stack-sorting map
European Journal of Combinatorics, 2021 17 pages, 4 ...
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, 1941 Date:1941Ella Stack and her family moved to Darwin in 1961. She was first employed for a few weeks mid-1961 by a local GP and then in 1962, Ella took over as long-term locum. She was one of two private practitioners in Darwin. Cyclone Tracy hit Darwin in
Stack, Ellen Mary
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
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NWIG, 2001 [First paragraph] Another year, another monumental stack of new books with Caribbeanist interest of one sort or another. NWIG reviewers have been contributing full essays on more than seventy such books each year, but that still leaves well over one
Richard Price, Sally Price
doaj
Deterministic stack-sorting for set partitions
Enumerative Combinatorics and Applications, 2023 A sock sequence is a sequence of elements, which we will refer to as socks, from a finite alphabet. A sock sequence is sorted if all occurrences of a sock appear consecutively. We define equivalence classes of sock sequences called sock patterns, which are in bijection with set partitions.
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FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
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FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
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