Results 81 to 90 of about 582,651 (294)

Extent of stacking disorder in diamond

open access: yes, 2015
Hexagonal diamond has been predicted computationally to display extraordinary physical properties including a hardness that exceeds cubic diamond. However, a recent electron microscopy study has shown that so-called hexagonal diamond samples are in fact ...
Murray, Benjamin J.   +2 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Stacking for Cosmic Magnetism with SKA Surveys

open access: yes, 2015
Stacking polarized radio emission in SKA surveys provides statistical information on large samples that is not accessible otherwise due to limitations in sensitivity, source statistics in small fields, and averaging over frequency (including Faraday ...
Keller, B. W., Stil, J. M.
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Wide-Area Subsidence Monitoring and Analysis Using Time-Series InSAR Technology: A Case Study of the Turpan Basin

open access: yesRemote Sensing
Ground subsidence often occurs over a large area. Although traditional monitoring methods have high accuracy, they cannot perform wide-area ground deformation monitoring.
Ruren Li   +3 more
doaj   +1 more source

Present-day crustal deformation around Kalpin block, Xinjiang, China, observed by InSAR

open access: yesGeodesy and Geodynamics, 2014
Due to the effect of the collision between the Indian plate and Eurasian plate, Pamirs is constantly moving to the north. Under the interaction among multiple tectonic blocks, strong earthquakes often occurred around the Kalpin block which is located in ...
Liu Liwei, Ji Lingyun, Yang Xiaodong
doaj   +1 more source

On the Stacking Charge Order in NaV2O5

open access: yes, 2004
We propose a mechanism for the observed stacking charge order in the quarter-filled ladder compound NaV2O5. Via a standard mapping of the charge degrees of freedom onto Ising spins we explain the stacking order as a result of competition between ...
Chitov, G. Y., Gros, C.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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