Results 161 to 170 of about 4,015,955 (267)

Detection of disease recurrence in real-world patients with completely resected stage III cutaneous melanoma. [PDF]

Acta Oncol
Peuranheimo T, Hellman A, Mäkelä S, Mattila K, Hernberg M.   +4 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Two-Stage Dynamic Synergistic Segmentation Method for Myocardial Pathology. [PDF]

J Imaging
Ruan D, Zhang X, Yuan Z, Lu Z, Xia L, Jiang M.   +5 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Transarterial Chemoembolization in Hepatocellular Carcinoma: Lessons from a 10-Year Real-World Retrospective Study. [PDF]

J Hepatocell Carcinoma
von Schoen-Angerer G, Pesola G, Garo ML, Marini G, Cappio S, Cerny A, Magenta L, Majno-Hurst P, Bernardi L, Cefalì M, Cristaudi A, Terziroli Beretta-Piccoli B, Trevisi E, De Dosso S.   +13 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Which immunonutritional marker best predicts disease-free survival in non-metastatic colorectal Cancer? The CALLY index and CAR emerge as independent predictors from a seven-marker comparison. [PDF]

Front Nutr
Lee JM, Kim T, Kim NK.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Superinfection and the hypnozoite reservoir for Plasmodium vivax: a multitype branching process approximation. [PDF]

J Math Biol
Mehra S, Taylor PG.
europepmc   +1 more source