Results 181 to 190 of about 4,015,955 (267)

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report. [PDF]

Bipolar Disord
Kupka R, Hafeman D, McCallum M, van der Markt A, Tremain H, Alda M, Almeida J, Cardoso TA, Balanzá-Martínez V, Birmaher B, Bond DJ, Brietzke E, Chendo I, Grande I, Hajek T, Hillegers M, Kauer-Sant'Anna M, Mansur R, Passos IC, Pinto AG, Post R, Tohen M, Vazquez G, Vieta E, Yatham LN, Kapczinski F, Berk M, Duffy A.   +27 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The reactivity of single magnesium nanoparticles towards corrosion and galvanic replacement.

Nanoscale
Brabant ALY, Knight PJ, Joyce KM, Elabbadi M, Lomonosov V, Boukouvala C, Ringe E.   +6 more
europepmc   +1 more source

DNA methylation clock in bull sperm cells reveals the epigenetic aging characteristics and impact on fertility. [PDF]

J Anim Sci Biotechnol
Li W, Tang Y, An S, Wang J, Feng X, Chen S, Yu Y.   +6 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Serum ferritin as a potential biomarker for distinguishing advanced-stage colorectal cancer: a retrospective cohort study. [PDF]

PeerJ
Cao C, Tang F, Zhu Z, Wang F, Li J.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Lobe-Specific Versus Systematic Lymph Node Dissection in Clinical Stage I Non-Small Cell Lung Cancer: A Propensity Score-Matched Analysis Based on the 8th Edition of the TNM Stage Classification. [PDF]

Thorac Cancer
Notsuda H, Onodera K, Kumata S, Kamata S, Kawakami T, Watanabe T, Watanabe Y, Hirama T, Suzuki T, Oishi H, Niikawa H, Okada Y.   +11 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A Two-Stage Classification Method for Improved Fault Detection in Wind Turbines Based on SCADA Data. [PDF]

Sensors (Basel)
Dai J, Rotea M, Kehtarnavaz N.
europepmc   +1 more source