Results 191 to 200 of about 3,846,815 (245)

Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study. [PDF]

PLoS Comput Biol
Braunack-Mayer L, Malinga J, Nekkab N, Kelly SL, Möhrle JJ, Penny MA.   +5 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Evaluation of immunohistochemical and gene expression of Janus kinase 1 and Janus kinase 3 in the skin of different clinical types of mycosis fungoides patients - Part 1. [PDF]

An Bras Dermatol
El-Amawy HS, Mohamed Ali BM, Shareef MM, Elgarhy L.   +3 more
europepmc   +1 more source

Perceived Ostomy odor and body image disturbance in colorectal cancer survivors: differences by ostomy status and sex. [PDF]

Support Care Cancer
Shin J, Yan G, Gibson JS, Jones RA, Gray M, Debnam KJ.   +5 more
europepmc   +1 more source

Neighborhood-Level Social Vulnerability, Race and Ethnicity, and Stage at Diagnosis: A Population-Based Study of 12,957 Patients with Oral Cavity Cancer. [PDF]

Cancer Epidemiol Biomarkers Prev
Tortolero GA, Sturgis EM, Yamal JM, Peskin MF, Bauer C, Murphy CC.   +5 more
europepmc   +1 more source

The phased characteristics and countermeasures of physical exercise behavior change of rural older adults in China. [PDF]

Front Public Health
Zhang WH, He CH, Lu WY, Zhang HP.
europepmc   +1 more source

Disparities in Diagnosis, Management, and Outcomes of Hepatocellular Carcinoma: A Review of Global and Sociodemographic Factors. [PDF]

J Gastrointest Cancer
Zheng C, Araque M, Quiej A, Buchanan-Peart KA, Jones PD.   +4 more
europepmc   +1 more source

Staged Total Hip Arthroplasty for Septic Hip Following Core Decompression in Sickle Cell-Related Osteonecrosis: A Case Report and Review of the Literature. [PDF]

Cureus
Alenezi M, Ayyad S, Alemairi T.
europepmc   +1 more source