Results 121 to 130 of about 11,193,863 (298)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Stability analysis in a delayed prey-predator-resource model with harvest effort and stage structure
In this paper, a prey-predator-resource model with harvest effort on resource biomass is proposed, where maturation delay and stage structure for prey population are considered. Positivity and boundedness of solutions are studied.
Yue, Wenquan +3 more
core
Wet on wet landscape of white, gray, green; blue houses; black foreground and blue sky. On same sheet as [Stage Two Landscapes 21].Tiff file: 2220x3330 pixels, 21.2 Mb; Display: jpeg, 533x800 pixels ...
Father Edward Catich
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Experimental Comparison of Multi-Stage and One-Stage Contests [PDF]
This article experimentally studies a two-stage elimination contest and compares its performance with a one-stage contest. Contrary to the theory, the two-stage contest generates higher revenue than the equivalent one-stage contest.
Roman M. Sheremeta
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Loan Market at the Current Stage: Structure and Features
This study examines the aspects of the functioning of the loan market at the current stage and analyzes its structure, features, and segments. Aim.
Egor A. Goncharuk
doaj
Regional climate affects salmon lice dynamics, stage structure and management. [PDF]
Hurford A, Wang X, Zhao XQ.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

