Results 101 to 110 of about 11,193,863 (298)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Harvesting of a Single-Species System Incorporating Stage Structure and Toxicity
Discrete Dynamics in Nature and Society, 2009 A single species stage-structured model incorporating both toxicant and harvesting is proposed and studied. It is shown that toxicant has no influence on the persistent property of the system.
Huiling Wu, Fengde Chen
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Permanence of predator-prey system with infinite delay
Electronic Journal of Differential Equations, 2004 In this paper we consider a predator-prey system with periodic coefficients and infinite delay, in which the prey has a history that takes them through two stages, immature and mature.
Jingan Cui, Yonghong Sun
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Gray, Wendell. Structure beneath Gray stage in Quidi Vidi.
, 2013 Support structure beneath the Gray stage, including pipes that run water and electricity from the Brewery to the ...
Sawden, Kari
core
STAGE - Data Management Plan n°1
The Data Management Plan (DMP) explains the management decisions made to ensure these aspects, as well as the preservation of the research products once the project ends.
Fras, Jeanne, Bardiot, Clarisse
core +2 more sources
Journal of Veterinary ResearchThe widespread distribution of the blood-sucking parasitic species Ashworthius sidemi among cervids highlights the need for increased understanding of how to prevent its transmission to livestock.
Kowal Jerzy +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source