Results 91 to 100 of about 11,193,863 (298)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Bifurcations of a modified Leslie–Gower predator–prey model with fear, Allee effect and hunting cooperation strategy

open access: yesJournal of Biological Dynamics
The fear preoften leads to changes in the physiological characteristics of the prey. Different stages of prey exhibit different physiological behaviours, such as susceptibility to predator risk, which often leads to Allee effect.
Weili Kong, Yuanfu Shao
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Asymptotic Behavior of Solutions to Delayed Nonlinear Integral Equations Influenced by Growth Rates and Time Delays

open access: yesMathematics
This study examines partial differential equation models with delay on both unbounded and bounded domains. The mathematical model is reformulated as a system of nonlinear integral equations.
Khalaf M. Alanazi
doaj   +1 more source

Optimal window structure option on the initial project stage [PDF]

open access: yesСтроительство уникальных зданий и сооружений, 2013
Prognostication of building energy consumption lets define its lowering ways possibility on the initial project stage by for example envelope isolation.
German Aleksandrovich Zelenov   +1 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A new structure for reconfigurable two-stage Nyquist pulse shaping filters

open access: yes, 2011
This paper introduces a new structure for reconfigurable two-stage finite-length impulse response (FIR) Nyquist filters using the Farrow structure. The Nyquist filter is split into two equal and linear-phase FIR spectral factors.
Tapio Saramaki   +5 more
core   +1 more source

Global dynamics of a predator-prey system with Holling type II functional response

open access: yesNonlinear Analysis, 2011
In this paper, a predator-prey system with Holling type II functional response and stage structure is investigated. By analyzing the corresponding characteristic equations, the local stability of each of feasible equilibria of the system is studied.
Xiaohong Tian, Rui Xu
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A stage structured predator–prey system with time delays and fear effect

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
In this study, we develop a delayed predator–prey model that incorporates two stage structures for both predator and prey populations, along with two constant maturation delays and fear effect.
Lingrui Li, Junli Liu, Tailei Zhang
doaj   +1 more source

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