Results 111 to 120 of about 1,716,518 (288)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

AN ECONOMIC INTERPRETATION OF IMPACT OF PHENOLOGICALLY TIMED IRRIGATION ON CORN YIELD [PDF]

An economic production function was derived in an analysis of water application to corn by phonological time periods. The quantities of use of water by growth periods as delineated by physical stages were tested for influence on final output of dry ...
Andersen, Jay C., Biswas, Basudeb, Gowon, Dawuda T.   +2 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Critical Periods During Childhood and Adolescence: A Study of Adult Height Among Immigrant Siblings [PDF]

We identify the ages that constitute critical periods in children's development towards their adult health status. For this we use data on families migrating into Sweden from countries that are mostly poorer, with less healthy conditions. Long-run health
Lundborg, Petter, Nystedt, Paul, Rooth, Dan-Olof, van den Berg, Gerard J.   +3 more
core  

Survey of Period Variations of Superhumps in SU UMa-Type Dwarf Novae. VIII: The Eighth Year (2015-2016)

, 2016
Continuing the project described by Kato et al. (2009, arXiv:0905.1757), we collected times of superhump maxima for 128 SU UMa-type dwarf novae observed mainly during the 2015-2016 season and characterized these objects.
Akazawa, Hidehiko, Ando, Kazuko, Andreev, Maksim V., Antipin, Sergey V., Antonyuk, Kirill A., Antonyuk, Oksana I., Babina, Julia V., Baklanov, Aleksei V., Bolt, Greg, Chochol, Drahomir, Cook, Lewis M., de Miguel, Enrique, Debski, Bartomiej, Dubois, Franky, Dubovsky, Pavol A., Dvorak, Shawn, Fukushima, Daiki, Gladilina, Natalia, Goff, William N., Golysheva, Polina, Hambsch, Franz-Josef, Hiraga, Mitsutaka, Hirosawa, Kenji, Horie, Tsuneo, Imada, Akira, Isogai, Keisuke, Itoh, Hiroshi, Kafka, Stella, Kamibetsunawa, Taku, Kasai, Kiyoshi, Kato, Taichi, Katysheva, Natalia, Kimura, Mariko, Kiyota, Seiichiro, Kochanek, Christopher S., Kojiguchi, Naoto, Kudzej, Igor, Logie, Ludwig, Maeda, Yutaka, Matsumoto, Katsura, Miller, Ian, Monard, Berto, Muyllaert, Eddy, Ogi, Minako, Oksanen, Arto, Otani, Noritoshi, Pavlenko, Elena P., Pickard, Roger D., Pit, Nikolaj V., Prieto, Jose L., Rau, Steve, Richmond, Michael, Ruiz, Javier, Sabo, Richard, Schmeer, Patrick, Shappee, Benjamin, Shears, Jeremy, Shugarov, Sergey Yu., Simon, Andrei, Sosnovskij, Aleksei A., Stanek, Krzysztof Z., Starr, Peter, Stein, William, Stone, Geoff, Stubbings, Rod, Sugiura, Yuki, Takeda, Nao, Takigawa, Naoki, Tanabe, Kenji, Tatsumi, Taiki, Tordai, Tamas, Uto, Yusuke, Vanaverbeke, Siegfried, Vanmunster, Tonny, Voloshina, Irina B., Yamada, Eiji, Zaostrojnykh, Anna M., Zubareva, Alexandra M.   +77 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Sexual stages of the female portion in the scallop Nodipecten nodosus (Linné, 1758) and astaxanthin quantity in each stage

Brazilian Journal of Biology
This work describes the gametogenic cycle of the scallop Nodipecten nodosus kept in a culture system. To this end, during one year, samples were taken from the broodstocks every 30 days to be submitted to macroscopic and microscopic analyses and to ...
S. Sühnel, F. Lagreze, M. Bercht, JF. Ferreira, AL. Carneiro-Schaefer, ARM. Magalhães, M. Maraschin   +6 more
doaj   +1 more source