We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Mouth Opened with Tongue Extended (MOTE) maneuver: improvement in tomographic T-staging accuracy of oral cavity cancer: a prospective cross-sectional study. [PDF]
Campos GF +10 more
europepmc +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The impact of FAPI PET on staging and management in patients with digestive system tumors: a systematic review and meta-analysis. [PDF]
Zou Y +5 more
europepmc +1 more source
E04-03: Advantages in surgical staging. Thoracoscopy or video-assisted thoracic surgery (VATS). [PDF]
Paul E. Van Schil
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Machine learning models based on log odds of positive lymph nodes for predicting survival in T<sub>1</sub>N<sub>+</sub> gastric cancer. [PDF]
Liu Y +7 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Proposed Development of a New Staging System for Hearing Loss: Countermeasure 2 of the Hearing Health Collaborative. [PDF]
Carlson ML +24 more
europepmc +1 more source

