Results 101 to 110 of about 87,457 (305)

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao   +5 more
wiley   +1 more source

Overcoming Stagnation in Metaheuristic Algorithms with MsMA’s Adaptive Meta-Level Partitioning

open access: yesMathematics
Stagnation remains a persistent challenge in optimization with metaheuristic algorithms (MAs), often leading to premature convergence and inefficient use of the remaining evaluation budget.
Matej Črepinšek   +5 more
doaj   +1 more source

THE RISKS ON THE RUSSIAN FINANCIAL MARKET IN THE CONDITIONS OF GLOBALIZATION

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article considers topical issues of functioning of the financial market in a globalized economy, approaches to determination of essence of the world financial market, classification of risks, inherent to the Russian financial market in terms of ...
Oliga Pakova   +2 more
doaj  

Physics‐Informed Neural Network‐Enabled Forward Prediction and Inverse Design of Ring Origami

open access: yesAdvanced Science, EarlyView.
This work presents a KRT‐PINN framework that integrates Kirchhoff rod theory with physics‐informed neural networks for the forward prediction and inverse design of ring origami consisting of closed‐loop rods. The framework predicts stable states of segmented rings with prescribed natural‐curvature profiles and determines the natural‐curvature profiles ...
Luyuan Ning   +3 more
wiley   +1 more source

Theories of economic growth and stagnation, with particular reference to China, 1840-1940

open access: yesPSL Quarterly Review, 2014
The paper provides a brief survey of certain significant contributions to the theory of economic growth and stagnation the further the study of a century of apparent stagnation in China.
N.T. WANG
doaj   +1 more source

Economic Stagnation Postponed [PDF]

open access: yesInternational Journal of Political Economy, 2011
The significant increase since the early 1980s in the share of income accruing to capital (rather than labor), in both the United States and the European Union, created the potential for economic stagnation. Stagnation was postponed, however, by the development of the banking sector in these countries, notably in the increasing amounts of credit ...
openaire   +3 more sources

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

open access: yesAdvanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo   +6 more
wiley   +1 more source

A Welfare Cost of the Lost Decade in Japan [PDF]

open access: yes
This paper measures the welfare cost of the Japanese economy in a elost decadef from 1990 to 2002, by using panels of different consumer groups. This paper finds that the costs for consumers in the lower and middle income quintiles and in urban districts
Tatsuyoshi Miyakoshi, Masakatsu Okubo
core  

Smart Exploration of Perovskite Photovoltaics: From AI Driven Discovery to Autonomous Laboratories

open access: yesAdvanced Energy Materials, EarlyView.
In this review, we summarize the fundamentals of AI in automated materials science, and review AI applications in perovskite solar cells. Then, we sum up recent progress in AI‐guided manufacturing optimization, and highlight AI‐driven high‐throughput and autonomous laboratories.
Wenning Chen   +4 more
wiley   +1 more source

THE RUSSIAN FEDERATION BEGINS THE 2016th: IS THE COUNTRY WAITING FOR THE ECONOMIC SLOWDOWN, DEPRESSION OR UPTURN?

open access: yesВестник университета, 2019
The review and the analysis of basic macroeconomic indicators for the Russian Federation are provided for determining the way of economic development in 2016.
T. Timashkova   +2 more
doaj  

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