Results 181 to 190 of about 383,377 (258)

IntAct-U-ExM enables super-resolution imaging of isoform-specific actin networks across species. [PDF]

PLoS Biol
Dhar A, Dey S, Mullick S, Suman NK, van Zwam MC, Palani Balaji NK, Ghosh A, Nair D, van den Dries K, Gadadhar S, Palani S.   +10 more
europepmc   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Control of Corrosion Resistance and Osteoclastic Resorbability of Bioresorbable Carbonate Apatite Coating for Biodegradable Mg Alloys through Carbonate Content. [PDF]

ACS Biomater Sci Eng
Hiromoto S, Midorikawa K, Yamazaki T, Yamamoto T.   +3 more
europepmc   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Distinct dendritic cell cytoskeletal programs dictate synapse architecture and CD8⁺ T cell fate. [PDF]

Front Immunol
Clamagirand CD, Ratswohl C, Schmid MW, Eich T, Anslinger N, Legler DF, Rossy J.   +6 more
europepmc   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

An Optimized Staining Method for Visualization of Thermally Denatured Dermal Collagen. [PDF]

Lasers Surg Med
Ahn GR, Quadri SA, Downs HM, T Suwan P, Wang-Evers M, Warner-Levy J, Manstein D.   +6 more
europepmc   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Providing maceration protocols for xylem and phloem research. [PDF]

Front Plant Sci
Romero E, Olson M, Segovia-Rivas A, Pittermann J, Jupa R.   +4 more
europepmc   +1 more source

Stained glass [PDF]

, 1900
openaire   +1 more source