Results 281 to 290 of about 3,617,008 (388)

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Diagnostic and prognostic utility of insulinoma-associated protein 1, insulin gene enhancer protein 1, and secretagogin in pheochromocytoma. [PDF]

Rev Assoc Med Bras (1992)
Sözen M, Turan G, Cantürk Z, Çetinarslan B, Selek A, Tosun M, Civriz AH, Sevinç B, Gezer E, Köksalan D.   +9 more
europepmc   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Towards a transcriptomic biomarker for the classification of melanocytic neoplasms. [PDF]

PLoS Genet
Borden ES, Hastings CT, Prakash N, Kuo T, Tapia E, Yozwiak M, Sagerman P, Vargas de Stefano D, Buetow KH, Wilson MA, Curiel-Lewandrowski C, Chow HS, LaFleur BJ, Hastings KT.   +13 more
europepmc   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Expression of gamma-aminobutyric acid type A receptor subunit π and minichromosome maintenance-3 in breast cancer patients treated with neoadjuvant chemotherapy: a target molecule or a proliferation marker? [PDF]

Rev Assoc Med Bras (1992)
İriagac Y, Oznur M, Çavdar E, Karaboyun K, Saray S, Avcı O, Şeber ES.   +6 more
europepmc   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Cdk5 Contributes to Diabetic Islet β Cell and Kidney Injury by Impairing Autophagy. [PDF]

FASEB J
Tao Y, Wang L, Liu Y, Wei Y, Wang R, Sha S, Zheng S, Hou S, Liu S.   +8 more
europepmc   +1 more source

THE EFFECT OF X-RAY ON THE SKIN OF VITALLY STAINED WHITE MICE

, 1924
Gerty T. Cori
openalex   +1 more source