Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim+8 more
wiley +1 more source
Decreased neuronal and increased endothelial fractalkine expression are associated with neuroinflammation in Parkinson's disease and related disorders. [PDF]
Chu Y+3 more
europepmc +1 more source
Label-Free Deep UV Microscopy in Oral Cytology: A Step Towards Stain-Free Diagnostics
Sumsum P. Sunny+10 more
openalex +1 more source
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Dynamics of amylopectin granule accumulation during the course of chronic <i>Toxoplasma</i> infection is linked to intra-cyst bradyzoite replication. [PDF]
Tripathi A+6 more
europepmc +1 more source
Which Chromium–Sulfur Compounds Exist as 2D Material?
2D chromium sulfides synthesized using molecular beam epitaxy on graphene. Structural characterization reveals two novel 2D materials, Cr2S3‐2D, which lacks a direct bulk counterpart, and Cr223S${\rm Cr}_{2\frac{2}{3}}{\rm S}$4‐2D, a minimum thickness version of Cr5S6. However, attempts to synthesize CrS2 are unsuccessful. Both new 2D phases are stable
Affan Safeer+5 more
wiley +1 more source
inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst. [PDF]
Nian K+6 more
europepmc +1 more source
Low‐Loss Far‐Infrared Surface Phonon Polaritons in Suspended SrTiO3 Nanomembranes
The low‐loss, highly confined, and thickness‐tunable surface phonon polaritons are demonstrated in the far‐infrared regime within transferable freestanding SrTiO3 membranes, achieving high figures of merit comparable to the previous record values from the vdW materials.
Konnor Koons+8 more
wiley +1 more source
Adipose tissue-associated Krt23+fibroblasts contribute to immune microenvironment disorders in mouse adipose tissue during the development of obesity. [PDF]
Lu Z+7 more
europepmc +1 more source