Results 231 to 240 of about 359,491 (304)

Safe and efficient intracellular delivery of functional antibodies into cultured neural cells shows a role for Alzheimer's-relevant tau phosphorylation in cell integrity. [PDF]

Front Dement
Viola KL, Chromy BA, Nowar R, Lambert MP, Klein WL.   +4 more
europepmc   +1 more source

Emergence of a Hexagonal Fe2S2 Single Layer Without a Bulk Counterpart via Phase Transformation

Advanced Functional Materials, EarlyView.
Upon annealing, single‐layer Mackinawite iron sulfide transforms into a previously unknown hexagonal Fe2S2${\rm Fe}_2{\rm S}_2$ phase with β$\beta$‐CuI structure. STM, LEED, and first‐principles calculations identify the structure and show that electronic correlations and magnetic order are important for its stability.
Affan Safeer, Wejdan Beida, Felix Oberbauer, Nicolae Atodiresei, Gustav Bihlmayer, Max Wolfertz, Chiara Schlichte, Wouter Jolie, Stefan Blügel, Jeison Fischer, Thomas Michely   +10 more
wiley   +1 more source

In Situ Interfacial Assembly of Dynamic Semi‐Interpenetrating Biopolymer Networks for Robust and Mechanically Adaptive Droplet Interfaces

Advanced Functional Materials, EarlyView.
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang, Yujie Liu, Yikai Xu, Xunda Feng, Ling Zhang, Hongbo Zeng, Hao Liu, Xiaohui Mao   +7 more
wiley   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Stress granules formed during infections with RNA viruses have significant virus-specific differences in generation and composition. [PDF]

PLoS Biol
Lang RM, Steiner S, Kelly J, Uldry AC, Dave P, Braga-Lagache S, Chao J, Heller M, Barut GT, Thiel V.   +9 more
europepmc   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

<i>direct</i> Stochastic Optical Reconstruction Microscopy to Determine the Oligomeric State of Proteins on the Plasma Membrane and Their Accessibility for Immunotherapeutic Antibodies. [PDF]

Bio Protoc
Eiring P, Doose S, Bauer N, Sauer M.
europepmc   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Towards reliable tracking of natural killer cells using commercial iron oxide nanoparticles and magnetic particle imaging.

Biomater Sci
Lightsey S, Consalvo V, Ali SR, Valdés DP, Oyer JL, Gloger G, Copik AJ, Rinaldi-Ramos C, Sharma B.   +8 more
europepmc   +1 more source

Aberrant ɑSMA expression reveals broad mossy fiber reorganization integrating with tangle and plaque formation and mitoenergetic alteration in the human hippocampus. [PDF]

Alzheimers Dement
Tu T, Zhang QL, Sun ZP, Kang C, Li D, Huo XH, Zhang XJ, Zhang Y, Cui M, Pan A, Wang J, Yan XX.   +11 more
europepmc   +1 more source