Results 41 to 50 of about 368,794 (339)
Exploration of High-Frequency Control of Dynamic Stall Using Large-Eddy Simulations
AIAA Journal, 2018 Dynamic stall represents a challenge in a number of engineering applications including rotorcraft, maneuvering aircraft, gust encounters, and wind turbines.
M. Visbal, S. Benton
semanticscholar +1 more source
Investigating the CREDIT History of Supernova Remnants as Cosmic-Ray Sources
The Astrophysical Journal LettersSupernova remnants (SNRs) have long been suspected to be the primary sources of Galactic cosmic rays. Over the past decades, great strides have been made in the modeling of particle acceleration, magnetic field amplification, and escape from SNRs.
Anton Stall +2 more
doaj +1 more source
Journal of Fluid Science and Technology, 2014 The effect of 3-dimensional blade on the turbine characteristics has been investigated experimentally by model testing under steady flow conditions and simulated numerically by quasi-steady analysis under sinusoidal flow conditions, in order to improve ...
Manabu TAKAO +3 more
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Computational research on the formation mechanism of double humps in pump–turbines
Engineering Applications of Computational Fluid Mechanics, 2021 The hump formation mechanism has not been fully understood so far, mainly because of two difficulties in analysis. The first one is how to find the most important external characteristic factor inducing humps, and the other is how to avoid too many ...
Yong Liu, Dezhong Wang, Hongjuan Ran
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Applied Sciences, 2021 Thick airfoils are conventionally adopted in the blade root region of a wind turbine to ensure structural safety under extreme conditions, despite the resulting power loss.
Hyeon-Gi Moon +3 more
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eLife, 2017 Ribosome stalling on mRNAs can decrease protein expression. To decipher ribosome kinetics at stall sites, we induced ribosome stalling at specific codons by starving the bacterium Escherichia coli for the cognate amino acid. We measured protein synthesis
Michael A. Ferrin, A. Subramaniam
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A stalled fork stalls recombination
The Journal of Cell Biology, 2005 Homologous recombination does not rescue stalled replication forks during S phase, report Meister et al. on page 537. Rather they find that replication and recombination are separated in terms of when and where they occur. If inappropriate recombination does occur when replication is stalled, replication forks fall apart.Researchers have debated ...
openaire +2 more sources