Results 71 to 80 of about 38,124 (276)

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Investigations on Quasi-Steady Characteristics for an Airfoil Oscillating at Low Reduced Frequencies

International Journal of Aerospace Engineering, 2010
Wind tunnel experiments were conducted on NACA-0015 airfoil model to investigate the effect of the reduced frequency (κ=0.0001 to 0.5) and that Reynolds number (Re=0.2E06 to 0.7E06) on the aerodynamic characteristics and hysteresis behavior associated ...
Deepakkumar M. Sharma, Kamal Poddar
doaj   +1 more source

An Approach to Detect Malicious Behaviors by Evading Stalling Code

TELKOMNIKA Indonesian Journal of Electrical Engineering, 2012
Since malwares contain stalling codes, malicious behaviors can’t be detected in emulated analysis environment. This paper proposes an approach to detect malicious behaviors by evade stalling codes. First, we executed a malware in the emulated analysis environment, and saved every executed instruction in a trace file; Second, we began to detect stalling
Chao You, Jianmin Pang, Yichi Zhang, Chao Dai, Xiaonan Liu   +4 more
openaire   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Corrective effect of many-body interactions in dynamical friction

, 2011
Dynamical friction is a fundamental and important phenomenon in astrophysics. The Chandrasekhar formula is a well-known analytical estimation of the effect.
Angus, Barnes, Barnes, Bekki, Binney, Binney, Boily, Buonanno, Buonanno, Burkert, Capuzzo-Dolcetta, Chandrasekhar, Cowsik, de Blok, de Blok, Durrell, Esquivel, Fujii, Fujii, Gilmore, Goerdt, Goerdt, Governato, Greco, Gualandris, Hashimoto, Hernandez, Hernquist, Inoue, Jiang, Kim, Li, Liu, Lotz, Lynden Bell, Mackey, Makino, Mashchenko, Mashchenko, Miller, Miocchi, Navarro, Oh, Ostriker, Pasetto, Pesce, Read, Salucci, Shigeki Inoue, Springel, Springel, Strader, Strigari, Sánchez-Salcedo, Tremaine, Tremaine, van Albada, Vesperini, Vesperini, Weinberg   +59 more
core   +1 more source

Isoperimetric behavior of generalized Stallings-Bieri groups

We introduce the notion of $n$-split for an epimorphism from a group to a finite rank free abelian group. This is used to provide bounds for the Dehn functions of certain coabelian subgroups of direct products of finitely presented groups. Such subgroups include and significantly generalize the Stallings-Bieri groups.
Brady, Noel, Goswami, Pratit, Merrell, Rob   +2 more
openaire   +2 more sources

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source

Astrocytic TIA1‐Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model

Advanced Science, EarlyView.
Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang, Xin Hua, Ziwei Fan, Jiaxin Zhao, Yuan Zhang, Qiaoyi Zhang, Xi Qu, Shengli Pan, Bingbing Wan, Shiyin Yang, Jia Li, Xu Zhang   +11 more
wiley   +1 more source

Enhancing Unmanned Aerial Vehicle Performance: A Comprehensive Review of Aerodynamic Improvement Techniques at Low Reynolds Numbers

International Journal of Aerospace Engineering
The increasingly prominent function of unmanned aerial vehicles (UAVs) across fields ranging from logistics and surveillance to farming and research calls for ongoing innovation in their flight efficiency. This study probes the effect of making strategic
Mohammad Hossein Moghimi Esfandabadi, Sohrab Panahandeh Taghi-Abad, Mohammad Hassan DJavarshakian   +2 more
doaj   +1 more source