Results 91 to 100 of about 2,940,165 (241)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Back End

, 2022
Artwork Index ...
Stance
core  

Lagged Stance Interactions and Counter-Spiral of Silence: A Data-Driven Analysis and Agent-Based Modeling of Technical Public Opinion Events

Systems
Understanding the dynamics of public opinion formation in digital environments is crucial for managing technological communications effectively. This study investigates stance interactions and opinion reversal phenomena in technical discourse through ...
Kaihang Zhang, Changqi Dong, Yifeng Guo, Wuai Zhou, Guang Yu, Jianing Mi   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

GPT outperforms BERT and LIWC for stance and anger detection in German news articles and user comments

Frontiers in Political Science
We live in an era of abundant qualitative language data that allows insights into societal trends and public attitudes, such as social media posts and news articles.
Lukas Mayrhofer, Markus Foramitti, Simon Fassnacht, Jana K. Köhler, Boryana Todorova, Claus Lamm, Mauricio Martins, Mauricio Martins, Mauricio Martins   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Quantum-Probability-Inspired Complex-Valued Model for Multilingual Stance Detection

Machine Learning and Knowledge Extraction
In this study, we propose a quantum-probability-inspired complex-valued model for multilingual stance detection. The model brings together ideas from granular computing and quantum theory to better capture semantic meaning across different languages. The
Muhammad Ebrahim Ahmadi, Monireh Hosseini   +1 more
doaj   +1 more source

Fake news stance detection using selective features and FakeNET. [PDF]

PLoS One, 2023
Aljrees T, Cheng X, Ahmed MM, Umer M, Majeed R, Alnowaiser K, Alnowaiser K, Abuzinadah N, Ashraf I.   +8 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Efficient Large-Scale Stance Detection in Tweets

, 2018
Stance detection is an important research direction which attempts to automatically determine the attitude (positive, negative, or neutral) of the author of text (such as tweets), towards a target.
Chen, Jonathan, Shyu, Mei-Ling, Yan, Yilin   +2 more
core   +1 more source