Results 81 to 90 of about 2,940,165 (241)

Back End

, 2023
Artwork Index ...
Stance
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Quantifying Variations in Controversial Discussions within Kuwaiti Social Networks

Big Data and Cognitive Computing
During the COVID-19 pandemic, pro-vaccine and anti-vaccine groups emerged, influencing others to vaccinate or abstain and leading to polarized debates.
Yeonjung Lee, Hana Alostad, Hasan Davulcu   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Front End

, 2022
About the Cover, Staff, Acknowledgments, Table of ...
Stance
core  

Bridging Ancient Wisdom and Modern Logic: Neutrosophic Perspectives on Body, Mind, Soul and Spirit [PDF]

Neutrosophic Sets and Systems
This study explores the application of neutrosophic logic to the interrelation of body, mind, soul, and spirit, proposing a fluid model that moves beyond traditional dualistic frameworks.
Florentin Smarandache, Maikel Y. Leyva Vázquez   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Front End

, 2021
About the Cover, Staff, Acknowledgments, Table of ...
Stance
core  

Modular Multi-Task Learning for Emotion-Aware Stance Inference in Online Discourse

Mathematics
Stance detection on social media is increasingly vital for understanding public opinion, mitigating misinformation, and enhancing digital trust. This study proposes a modular Multi-Task Learning (MTL) framework that jointly models stance detection and ...
Sio-Kei Im, Ka-Hou Chan
doaj   +1 more source