Results 121 to 130 of about 2,953,852 (350)

prfectBLAST: a platform-independent portable front end for the command terminal BLAST+ stand-alone suite

open access: yesBioTechniques, 2012
prfectBLAST is a multiplatform graphical user interface (GUI) for the stand-alone BLAST+ suite of applications. It allows researchers to do nucleotide or amino acid sequence similarity searches against public (or user-customized) databases that are ...
Perfecto Santiago-Sotelo   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

High-Tc superconducting THz emitters fabricated by wet etching

open access: yesAIP Advances, 2019
We studied the etching of small crystals of the high-Tc superconductor Bi2Sr2CaCu2O8+δ (Bi2212) with various dilute compositions of hydrochloric and nitric acids.
Yuuki Shibano   +8 more
doaj   +1 more source

Ownership links, leverage and credit risk [PDF]

open access: yes
This paper explores the relationship between optimal leverage and credit risk under ownership links. It develops a structural model of a parent and a subsidiary, which issues debt in its own name under a guarantee by the parent.
Elisa Luciano, Giovanna Nicodano
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

National economic policy simulations with global interdependencies : a sensitivity analysis for Germany [PDF]

open access: yes
"Policy simulations for national economies with econometric models in general are done using a stand alone national model with exogenous export values and import prices. In a globalised world such an exercise is critical, since the policy in question may
Lutz, Christian   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A comprehensive sizing methodology for stand-alone battery-less photovoltaic water pumping system under the Egyptian climate

open access: yesCogent Engineering, 2016
This work introduces comprehensive sizing methodology to optimize a stand-alone battery-less PV water pumping system (PVWPS). The essential target for the battery-less PVWPS is storing water instead of electrical energy. The drawback of employing battery
Hegazy Rezk
doaj   +1 more source

Analysis of Petri Nets and Transition Systems

open access: yes, 2015
This paper describes a stand-alone, no-frills tool supporting the analysis of (labelled) place/transition Petri nets and the synthesis of labelled transition systems into Petri nets.
Best, Eike, Schlachter, Uli
core   +2 more sources

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