Results 101 to 110 of about 11,437,124 (248)

The influence of stand spatial structure on understory sapling species diversity in natural forests of Qujiang District

Ecological Indicators
Understory sapling regeneration is crucial for maintaining the stability and functioning of forest ecosystems. To investigate the mechanisms through which stand spatial structure influences understory sapling species diversity and to identify key driving
Jian Liang, Yitian Chai, Yixin Wu, Jiaxi He, Yufeng Zhou, Yongjun Shi   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Drivers of aboveground biomass along riparian gradients in desert

Forest Ecosystems
Populus euphratica is a key dominant tree species in desert riparian forests, and the formation and maintenance of its aboveground biomass (AGB) are important for sustaining ecosystem functioning in arid regions.
Houji Liu, Jie Wang, Zhikun Yang, Lijun Zhu, Juntuan Zhai, Zhijun Li   +5 more
doaj   +1 more source

Local-Scale Patterns of Genetic Variability, Outcrossing, and Spatial Structure in Natural Stands of Arabidopsis thaliana

PLoS Genetics, 2010
As Arabidopsis thaliana is increasingly employed in evolutionary and ecological studies, it is essential to understand patterns of natural genetic variation and the forces that shape them. Previous work focusing mostly on global and regional scales has demonstrated the importance of historical events such as long-distance migration and colonization ...
Bomblies, Kirsten, Yant, Levi, Laitinen, Roosa A., Kim, Sang-Tae, Hollister, J, Warthmann, Norman, Fitz, Joffrey, Weigel, Detlef   +7 more
openaire   +8 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Dynamic optimization of stand structure in Pinus yunnanensis secondary forests based on deep reinforcement learning and structural prediction

Frontiers in Plant Science
IntroductionThe rational structure of forest stands plays a crucial role in maintaining ecosystem functions, enhancing community stability, and ensuring sustainable management.
Jian Zhao, Jianming Wang, Jiting Yin, Yuling Chen, Baoguo Wu   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Investigation on structure of oriental beech (Fagus orientalis Lipsky) stand at optimal stage in Sangdeh forest [PDF]

تحقیقات جنگل و صنوبر ایران, 2010
In order to study the spatial structure of oriental beech (Fagus orientalis Lipsky) stand at optimal stage, this research was carried out in the Caspian forests of Iran. The studied site consisted of a natural stand located at Sangdeh district (Mers-e-se)
Majied Hassani, Manoochehr Amani
doaj