Results 191 to 200 of about 6,801,757 (235)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Protocol for ex vivo physicochemical assessment of photothermally preconditioned platelet-rich plasma. [PDF]

MethodsX
Cordero L, Sánchez-Vizcaíno Mengual E, Pinto H.   +2 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Screening and validation of rabbit monoclonal antibody pair against human FGF21 for human plasma FGF21 high sensitivity bioanalysis. [PDF]

iScience
Zhao S, Ji Z, Wang Y, Li J, He Y, Shen J, Liu C, Wang L, Ma X, Wang S, He J, Xu F.   +11 more
europepmc   +1 more source

Authors' Reply: Beyond Visual Consensus: Tiered Reference Framework for AI Cystoscopy Studies. [PDF]

J Med Internet Res
Tsai CY, Huang SW.
europepmc   +1 more source

A 3.5-minute-long reading-based fMRI localizer for the language network. [PDF]

Imaging Neurosci (Camb)
Tuckute G, Lee EJ, Sathe A, Fedorenko E.
europepmc   +1 more source

The Effect of the Temporal Position of a Gap on Its Automatic Detection. [PDF]

Eur J Neurosci
Omidvar S, Campbell K, Alain C, Aiken S, Koravand A.   +4 more
europepmc   +1 more source

Effect of low-level laser therapy versus calcium hydroxide intra-canal medication on postoperative pain and inflammatory mediator reduction in symptomatic apical periodontitis: a randomized clinical trial. [PDF]

BMC Oral Health
Otaify RR, Abouelenien SS, Ghoneim AG, Shaker OG.   +3 more
europepmc   +1 more source