Results 71 to 80 of about 6,707,439 (298)
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio+9 more
wiley +1 more source
Identification and Quantification of 5-Hydroxymethyl Furfural in Food Products
5-Hydroxymethylfurfural (5-HMF) is known as an indicator of quality deterioration in a wide range of foods. The current study covered 70 samples taken from domestically produced foods and drinks available on the Iranian markets (including honey, jam ...
Maryam Jalili, Farzaneh Ansari
doaj
No Standard for Standards: Understanding the ICT Standards Development Ecosystem
There is no standard for standards. Technology standards are created, maintained and propagated in a bewildering variety of ways, by a diverse set of actors. This Chapter attempts to explain this ironic and complex reality, and to provide a framework for understanding different standards development models in the information and communications ...
openaire +4 more sources
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki+4 more
wiley +1 more source
Quality Status and Skin-Related Functional Properties of Traditional Korean Fermented Vinegars
The correlation between fermented vinegar’s physicochemical properties and functional characteristics, particularly skin-related functionalities, remains unclear.
Hwan Hee Yu+4 more
doaj +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran+6 more
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
An Investigation of the League of Nations Standard Requirements for Schick Toxin [PDF]
E. M. Taylor, P. J. Moloney
openalex +1 more source
This paper provides a review of the current state of the art in standards for Public Key Infrastructures. The main focus of the paper is the recent work by the Internet Engineering Task Force, ITU-T, and ISO/IEC.
openaire +6 more sources