Results 161 to 170 of about 1,521,543 (298)

Consistency in staging, grading, and extent of periodontitis diagnosis: A cross-sectional online-based assessment among Indonesian periodontics specialist students. [PDF]

Medicine (Baltimore)
Wijaksana IKE, Hepitaria NA, Savitri IJ, Abullais SS, AlQahtani S, Bahamdan GK.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

International standards and agreements in food irradiation

, 2006
The economies of both developed and developing countries have been affected by their exported food and agricultural products. Trading policies of food and agricultural products are governed by international agreement as well as national regulations.Trade in food and agricultural commodities may be affected by both principal Agreements within the ...
openaire   +1 more source

On the usefulness of Thompson´s test with a four-point scale after Achilles tendon rupture, a pilot study. [PDF]

BMC Musculoskelet Disord
Wetterteg AL, Riad J, Nordin P.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Framework for a standard form of joint venture agreement for construction works

, 2010
The absence of a standard form of joint venture agreement for construction works has led parties intending to form a joint venture to resort to custom-made or in-house agreement often drafted by the parties themselves.
Samsuddin, Mohamad Shafiq Amin, Hasan, Sharina Farihah, Abdul Rashid, Khairuddin   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Role of standards in trade agreements

First report on role of standards in trade agreements with target countries with ...
openaire   +1 more source

Nonstandard Agreement in Standard English: The Social Perception of Agreement Variation under Existential there

, 2016
When using existential constructions to introduce plural NPs (e.g., there are dishes in the sink), speakers have the option of using a plural or singular form of the verb.
Hilton, Katherine
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source