Results 191 to 200 of about 2,624,056 (297)

iSIM-Sigma: Efficient Standard Deviation Calculation for Molecular Similarity. [PDF]

J Chem Inf Model
Lopez-Perez K, Zhao B, Miranda-Quintana RA.   +2 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Moving standard deviation assisted two-terminal traveling wave based fault location estimation technique for transmission system incorporated with UPFC. [PDF]

Sci Rep
Mishra S, Kumar R, Kumari S, Khanna A, Prakash T, Dewangan NK.   +5 more
europepmc   +1 more source

Simplified Optimal Estimation of Time-Varying Electromyogram Standard Deviation (EMGσ): Evaluation on Two Datasets. [PDF]

Sensors (Basel), 2021
Wang H, Rajotte KJ, Wang H, Dai C, Zhu Z, Huang X, Clancy EA.   +6 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Standard deviation of pulse pressure measured using wearable devices improves the estimation of acute psychological stress. [PDF]

Sci Rep
Shiotani T, Minakata M, Toyoda E, Odane C, Mitsuyasu U, Nakao T.   +5 more
europepmc   +1 more source

The Unsupervised Feature Selection Algorithms Based on Standard Deviation and Cosine Similarity for Genomic Data Analysis. [PDF]

Front Genet, 2021
Xie J, Wang M, Xu S, Huang Z, Grant PW.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Dimensionality reduction in hyperspectral imaging using standard deviation-based band selection for efficient classification. [PDF]

Sci Rep
Kurz W, Wang K, Bektas F, Zhu C, Kariper E, Dong X, Kurz M, Jakobi M, Baranes D, Koch AW.   +9 more
europepmc   +1 more source

Numerical Analysis of the Heterogeneity Effect on Electroosmotic Micromixers Based on the Standard Deviation of Concentration and Mixing Entropy Index. [PDF]

Micromachines (Basel), 2021
Farahinia A, Jamaati J, Niazmand H, Zhang W.   +3 more
europepmc   +1 more source