Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Predicting Pattern Standard Deviation in Glaucoma: A Machine Learning Approach Leveraging Clinical Data. [PDF]
Vision (Basel)Remtulla R +5 more
europepmc +1 more source
Association of Hemoglobin to Red Blood Cell Distribution Width-Standard Deviation (RDW-SD) Ratio and 3-Month Readmission in Elderly Chinese Patients with Heart Failure: A Retrospective Cohort Study. [PDF]
Int J Gen Med, 2023 Song J, Yu T, Yan Q, Zhang Q, Wang L.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Predictive Modeling of Central Precocious Puberty Using IGF-1 and IGFBP-3 Standard Deviation Scores. [PDF]
Diagnostics (Basel)Choi R, Chun G, Cho SE, Lee SG.
europepmc +1 more source
ABCMETAapp: R shiny application for simulation-based estimation of mean and standard deviation for meta-analysis via approximate Bayesian computation. [PDF]
Res Synth Methods, 2021 Kwon D, Reddy RRS, Reis IM.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Background Pixel Removal for Near-Infrared Hyperspectral Images Based on the Pixel-Wise Standard Deviation of Reflectance. [PDF]
Appl SpectroscGenkawa T, Ikehata A.
europepmc +1 more source
Lyophilization and homogenization of biological samples improves reproducibility and reduces standard deviation in molecular biology techniques. [PDF]
Amino Acids, 2021 Molnar A +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source