Results 41 to 50 of about 166,380,555 (243)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Block-Run Run-Length Coding of Handwriting and Bilevel Graphics Based on Quadtree Segmentation

, 1997
An efficient off-line coding scheme for handwriting and bilevel graphics based on quadtree segmentation and block-run run-length coding (RLC) is presented.
Yuen, H, Hanzo, L
core   +1 more source

Cumulative Sum Chart Modeled under the Presence of Outliers

Mathematics, 2020
Cumulative sum control charts that are based on the estimated control limits are extensively used in practice. Such control limits are often characterized by a Phase I estimation error.
Nasir Abbas, Mu’azu Ramat Abujiya, Muhammad Riaz, Tahir Mahmood   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Exponentially weighted moving average-Moving average charts for monitoring the process mean.

PLoS ONE, 2020
This research aimed to propose a newly-mixed control chart called the Exponentially Weighted Moving Average-Moving Average Chart (EWMA-MA) to detect the mean change in a process underlying symmetric and asymmetric distributions.
Saowanit Sukparungsee, Yupaporn Areepong, Rattikarn Taboran   +2 more
doaj   +1 more source

Monitoring multinomial processes based on a weighted chi-square control chart

Gestão & Produção, 2021
: Interpreting an out-of-control signal is a crucial step in monitoring categorical processes. For the Chi-Square Control Chart (CSCC), an out-of control situation does not specify if it was a process deterioration or a process improvement.
Achouri Ali, Emira Khedhiri, Ramzi Talmoudi, Hassen Taleb   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Modified Double Sampling Coefficient of Variation Control Chart

Journal of Mathematical and Fundamental Sciences, 2023
The concept of monitoring the coefficient of variation has gained significant interest in quality control, particularly in situations where the mean and standard deviation of a process are not constant.
Fachrur Rozi, Udjianna Sekteria Pasaribu, Utriweni Mukhaiyar, Dradjad Irianto   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

New Cumulative Sum Control Chart for Monitoring Poisson Processes

IEEE Access, 2017
The cumulative sum (CUSUM) control charts are widely used for measurement control of continuous processes. However, the quality characteristics of interest in many production processes, follows a sequence of discrete counts for non-conformities often ...
Mu'azu Ramat Abujiya
doaj   +1 more source