Results 141 to 150 of about 1,161,301 (313)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Estimates of genetic correlations and their standard error of estimates between meat quality and performance traits.

, 2014
1See Table 6 for trait abbreviation definitions.2 The significant correlations are bolded ...
Graham Plastow (174335), Stephen Moore (233604), Robert Kemp (650539), Abe Huisman (650541), Heather Bruce (650537), Zhiquan Wang (38051), Younes Miar (650536), Ghader Manafiazar (650538), Benny van Haandel (650542), Robert McKay (650543), Chunyan Zhang (30676), Patrick Charagu (650540)   +11 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Analysis of statistical methods for estimating standard radiation doses for patients undergoing computed tomography at the A.I. Burnazyan Federal Medical Biophysical Center

Радиационная гигиена
This study compares standard radiation dose estimates for patients undergoing computed tomography (CT) of major anatomical regions at the A.I. Burnazyan Federal Medical Biophysical Center using three different statistical approaches.
E. I. Matkevich, A. G. Sivenkov, A. N. Bashkov, A. S. Samoylov   +3 more
doaj   +1 more source

Elliptic interpolation estimates for non-standard growth operators

, 2014
We derive a class of potential estimates for elliptic equations with non-standard growth having a measure on the right-hand side; in particular our results allow to interpolate between the pointwise estimates available for solutions to this equation and ...
Baroni, Paolo,, BARONI, PAOLO, HABERMANN J., Habermann, Jens, Paolo Baroni, Jens Habermann   +5 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

On the use of the healthy lifestyle index to investigate specific disease outcomes

Scientific Reports
The healthy lifestyle index (HLI), defined as the unweighted sum of individual lifestyle components, was used to investigate the combined role of lifestyle factors on health-related outcomes.
Vivian Viallon, Heinz Freisling, Komodo Matta, Anne Østergaard Nannsen, Christina C. Dahm, Anne Tjønneland, Anne Kirstine Eriksen, Rudolf Kaaks, Verena A. Katzke, Matthias B. Schulze, Giovanna Masala, Giovanna Tagliabue, Vittorio Simeon, Rosario Tumino, Lorenzo Milani, Jeroen W. G. Derksen, Yvonne T. van der Schouw, Therese Haugdahl Nøst, Kristin Benjaminsen Borch, Torkjel M. Sandanger, J. Ramón Quirós, Miguel Rodriguez-Barranco, Catalina Bonet, Amaia Aizpurua-Atxega, Lluís Cirera, Marcela Guevara, Björn Sundström, Anna Winkvist, Alicia K. Heath, Marc J. Gunter, Elisabete Weiderpass, Mattias Johansson, Pietro Ferrari   +32 more
doaj   +1 more source

Attribute estimates (standard errors) of the MIXL model.

, 2014
**Significant at ...
G. Ardine de Wit (245519), Mattijs S. Lambooij (603801), Esther W. de Bekker-Grob (573915), Henriëtte A. Smit (5227754), Jorien Veldwijk (653944)   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

An artificial standard for use in the estimation of haemoglobin [PDF]

Biochemical Journal, 1945
Q H, Gibson, D C, Harrison
openaire   +2 more sources