Effectiveness-implementation trial comparing a family model of diabetes self-management education and support with a standard model. [PDF]
Mayberry LS +10 more
europepmc +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Research on denoising method of chinese ancient character image based on chinese character writing standard model. [PDF]
Yalin M, Li L, Yichun J, Guodong L.
europepmc +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Checking the 8Be Anomaly with a Two-Arm Electron Positron Pair Spectrometer
We have repeated the experiment performed recently by ATOMKI Laboratory (Debrecen, Hungary), which may indicate a new particle called X17 in the literature.
Tran The Anh +11 more
doaj +1 more source
Study of the standard model with weak decays of charmed hadrons at BESIII. [PDF]
Li HB, Lyu XR.
europepmc +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Linking the supersymmetric standard model to the cosmological constant. [PDF]
Qiu YC, Tye SH.
europepmc +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
In this brief paper, I give a very personal account on the state of particle physics on the occasion of Paul Frampton’s 80th birthday.
Xavier Calmet
doaj +1 more source

