Results 161 to 170 of about 4,031,297 (266)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Precise standard-model predictions for polarised Z-boson pair production and decay at the LHC. [PDF]

open access: yesEur Phys J C Part Fields
Carrivale C   +21 more
europepmc   +1 more source

ε ' / ε in the Standard Model at the Dawn of the 2020s. [PDF]

open access: yesEur Phys J C Part Fields, 2020
Aebischer J, Bobeth C, Buras AJ.
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Linearly homomorphic aggregate signature secure in the standard model

open access: yesTongxin xuebao
Existing lattice-based linear homomorphic signature schemes have difficulty in balancing multi-user aggregation and provable security under the standard model, which limits their practical application in real-world distributed scenarios.
HAN Yiliang   +4 more
doaj  

Searches for physics beyond the standard model with the M T 2 variable in hadronic final states with and without disappearing tracks in proton-proton collisions at s = 13 Te . [PDF]

open access: yesEur Phys J C Part Fields, 2020
Sirunyan AM   +2316 more
europepmc   +1 more source

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