Results 171 to 180 of about 4,204,163 (266)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Precise standard-model predictions for polarised Z-boson pair production and decay at the LHC. [PDF]

open access: yesEur Phys J C Part Fields
Carrivale C   +21 more
europepmc   +1 more source

ε ' / ε in the Standard Model at the Dawn of the 2020s. [PDF]

open access: yesEur Phys J C Part Fields, 2020
Aebischer J, Bobeth C, Buras AJ.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Searches for physics beyond the standard model with the M T 2 variable in hadronic final states with and without disappearing tracks in proton-proton collisions at s = 13 Te . [PDF]

open access: yesEur Phys J C Part Fields, 2020
Sirunyan AM   +2316 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

FURTHER STUDY OF THE HIGGS BOSON PROPERTIES, SUCH AS ITS COUPLINGS AND POTENTIAL DEVIATIONS FROM THE STANDARD MODEL PREDICTIONS

open access: yesWorldwide Journal of Physics
The study of the Higgs boson, a fundamental particle of the Standard Model of particle physics, continues to be a focal point of scientific inquiry. This abstract highlights ongoing research aimed at unraveling the Higgs boson's properties, particularly ...
Iqbal Ahmed   +2 more
doaj  

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