Results 111 to 120 of about 6,793,295 (290)

EFFECT OF GARLIC POWDER (ALLIUM SATIVUM LINN) ON REDUCING THE SIGN AND SYMPTOMS OF PULMONARY TUBERCULOSIS

Jurnal Ilmiah Kesehatan
Garlic contains substances that function as broad-spectrum antimicrobials that can inhibit the bacteria that cause Tuberculosis (TB). The purpose of this study was to explain the effect of providing garlic powder (Allium Sativum Linn) on reducing the ...
Retno Twistiandayani Retno, Istiroha, Akhmat Imam Lajuward   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Membrane Fouling and Chemical Cleaning in Three Full-Scale Reverse Osmosis Plants Producing Demineralized Water

Journal of Engineering, 2017
Membrane fouling and cleaning were studied in three reverse osmosis (RO) plants. Feed water was secondary wastewater effluent, river water, and surface water. Membrane autopsies were used for fouling characterization.
Florian Beyer, Judita Laurinonyte, Arie Zwijnenburg, Alfons J. M. Stams, Caroline M. Plugge   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Maintainability Analysis of Remotely Operated LNG Marine Loading Arms Based on UNE 151001 Standard

Machines
The operation of liquefied natural gas (LNG) marine loading arms plays a pivotal role in the efficient transfer of LNG from maritime vessels to downstream facilities, underpinning the global LNG supply chain.
Fabian Orellana, Orlando Durán, José Ignacio Vergara, Adolfo Arata   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Interpretation of the group standard for operation procedure of meibomian gland massage

Yanke Xuebao
Meibomian gland dysfunction (MGD) can lead to an imbalance in the ocular surface microenvironment,eye discomfortable, and visual impairment, thereby profoundly affecting the visual quality of life of patients.Meibomian gland massage is now widely used in
TIAN Bishan, LI Shuping, FU Qi, DENG Yuqing, XIAO Bing, YUAN Jin   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source