Results 121 to 130 of about 6,793,295 (290)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
SystemsStandard Operating Procedures (SOPs) serve a critical role in complex systems operations, guiding operator response during normal and emergency scenarios. This study compares 29 SOPs (517 steps) across three domains with varying operator selection rigor:
Jomana A. Bashatah, Lance Sherry
doaj +1 more source
Standard operating procedures for UAV or drone based\ud monitoring of wildlife [PDF]
, 2017 This paper summarises a Standard Operating Procedure (SOP) and recommended practices for the use of UAVs or Drones for wildlife monitoring. These include some of the technological changes required to minimise impact, as well as operational considerations
Johnson, Sandra, Gonzalez, Felipe
core +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Standard Operating Procedures [PDF]
, 2007 Robert D. Christ, Robert L. Wernli Sr
openaire +2 more sources
Clips: a capacity and lead time integrated procedure for scheduling. [PDF]
We propose a general procedure to address real life job shop scheduling problems. The shop typically produces a variety of products, each with its own arrival stream, its own route through the shop and a given customer due date.
Lambrecht, Marc +2 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Applied SciencesThis article deals with the analysis of the accuracy of the geodetic real-time GNSS measurement procedure used in railway operating conditions in the Czech Republic. The purpose was to determine to what extent the operating conditions affect the accuracy
Jiri Bures +4 more
doaj +1 more source