Results 51 to 60 of about 4,403,116 (314)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Automatic Prediction of Protein 3D Structures by Probabilistic Multi-template Homology Modeling. [PDF]

open access: yesPLoS Computational Biology, 2015
Homology modeling predicts the 3D structure of a query protein based on the sequence alignment with one or more template proteins of known structure.
Armin Meier, Johannes Söding
doaj   +1 more source

RTB Innovation Catalog Template

open access: yes, 2022
The template can be used for the documentation of innovations in the CGIAR Research Program on Roots, Tubers and Bananas (RTB) Innovation Catalog. The template explains what information and fields to provide and how to provide it in order to successfully
Clarke, Victoria
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Evaluation of template‐based models in CASP8 with standard measures [PDF]

open access: yesProteins: Structure, Function, and Bioinformatics, 2009
AbstractThe strategy for evaluating template‐based models submitted to CASP has continuously evolved from CASP1 to CASP5, leading to a standard procedure that has been used in all subsequent editions. The established approach includes methods for calculating the quality of each individual model, for assigning scores based on the distribution of the ...
Domenico Cozzetto   +5 more
openaire   +4 more sources

Formulir Berlangganan, Template, Pedoman Penulisan

open access: yes, 2018
Formulir Berlangganan, Template, Pedoman ...
Pedoman Penulisan, Formulir Berlangganan, Template,
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Statistical Structural Analysis of Familial Spontaneous Epileptic Cats Using Voxel-Based Morphometry

open access: yesFrontiers in Veterinary Science, 2018
Voxel-based morphometry (VBM) based on high resolution three-dimensional data of magnetic resonance imaging has been developed as a statistical morphometric imaging analysis method to locate brain abnormalities in humans.
Yuji Hamamoto   +8 more
doaj   +1 more source

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