Results 91 to 100 of about 173,214 (212)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
World Exhibitions and Educational Nation-Building. French Teacher Delegations to Paris in 1867
CabásNineteenth century world exhibitions served as meta-media for the circulation of educational knowledge. Focusing on the Exposition universelle in Paris in 1867, this article discusses how the French Ministry of Public Instruction made use of the ...
Klaus Dittrich
doaj +1 more source
Revue d'anthropologie des connaissances, 2019 Now commonly adopted as the point of reference for musicians in the Western world, A 440hz only became the standard pitch during an international conference held in London in 1939.
Fanny Gribenski
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Alternative sources of data for alternative histories of standardisation
Language Policy, 2019 What almost all accounts of standardisation histories have in common is a focus on printed, formal or literary texts from writing elites. While Haugen identified the written form of a language as “a significant and probably crucial requirement for a ...
Stephan Elspass
semanticscholar +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
ClíoThe aim was a comparative analysis of key characteristics of educational system governance, funding models, quality assurance approaches, language policy, inclusive education, and adult education in Albania, North Macedonia, Montenegro, and Serbia.
Hodaj Albana, Billa Enkelejda
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Digital Clients: An Example of People Production in Social Work
Social Inclusion, 2019 Digital work has become part of social workers’ daily routines in countries where digitalisation is on the agenda. As a consequence, documentation practices are expanding—on paper as well as digitally—and include reporting detailed statistics about ...
Elizabeth Martinell Barfoed
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
IET Networks, 2016 The standardisation of the 10 GB‐capable passive optical network (XG‐PON) system is accompanied by a rigorous set of recommendations. Power reduction in XG‐PONs is considered a quite important topic by the telecommunication standardisation sector (ITU‐T),
Panagiotis Sarigiannidis +3 more
doaj +1 more source