Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Typical public institutions such as government offices, hospitals, and schools play important leading and exemplary roles in the green and low-carbon development of the whole society.
Lan Zhang, Rui Zhang, Yuexin Ma, Yan Bai
doaj +1 more source
Standardized Treatment and Assessment Pathway Improves Mortality in Adults With Methicillin-resistant Staphylococcus aureus Bacteremia: STAPH Study [PDF]
Sara Alosaimy +15 more
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Transformation Path for Agricultural Whole Chain Standardization
Agricultural whole chain standardization (AWCS) is crucial for ensuring the security and stability of the agricultural industry of China and for promoting the transformation and upgrading of the industry.
Yan Yanhua +7 more
doaj +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Imaging Quality and Fatigue Quantification of Ocular Optical System
Human eye is a special kind of optical system, and its imaging quality and fatigue level seem susceptible to the illumination. In this study we were sought to develop a novel method to quantify ocular fatigue more accurately, and to assess the influence ...
Jianqi Cai +4 more
doaj +1 more source
Antioxidant Efficacy of a Standardized Red Orange (Citrus sinensis (L.) Osbeck) Extract in Elderly Subjects: A Randomized, Double Blind, Controlled Study [PDF]
Vincenzo Nobile +5 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
STANDARDIZATION OR ADAPTATION IN COSMETICS WEBSITES MARKETING ? AN EMPIRICAL STUDY [PDF]
The websites marketing is becoming an important tool both for multinationals and SMEs, in their effort to internationalizing their business. This study focuses on the international opportunities that are present within the European markets.
Anca Constantinescu-Dobra
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