Results 61 to 70 of about 2,123,410 (338)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

60 GHz MAC Standardization: Progress and Way Forward

open access: yes, 2015
Communication at mmWave frequencies has been the focus in the recent years. In this paper, we discuss standardization efforts in 60 GHz short range communication and the progress therein.
Cao, Zizheng   +4 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Current Situation, Problem Analysis and Prospect of Health Food Standardization in China Based on High Quality Development

open access: yesShipin gongye ke-ji, 2023
Health food, which is a specific type of food, plays an important role in chronic disease prevention, health promotion and life quality improvement. In order to promote the healthy, sustainable and high-quality development of Chinese health food industry,
Zhenyu YUN   +4 more
doaj   +1 more source

Data standardization [PDF]

open access: yes, 2019
With data rapidly becoming the lifeblood of the global economy, the ability to improve its use significantly affects both social and private welfare.
Gal, MS, Rubinfeld, DL
core  

Reference Standardization for Quantification and Harmonization of Large-Scale Metabolomics.

open access: yesAnalytical Chemistry, 2020
Reference standardization was developed to address quantification and harmonization challenges for high-resolution metabolomics (HRM) data collected across different studies or analytical methods.
Ken H. Liu   +7 more
semanticscholar   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Unstandard Standardization: The Case of Biology [PDF]

open access: yes, 2010
How applicable are the approaches adopted by information and communication technology standards-setting organizations to biological standards? Most engineering-based industries construct products from standard, well understood components.
Rai, Arti K.
core   +1 more source

Variability and Standardization of Quantitative Imaging

open access: yesInvestigative Radiology, 2020
Radiological images have been assessed qualitatively in most clinical settings by the expert eyes of radiologists and other clinicians. On the other hand, quantification of radiological images has the potential to detect early disease that may be ...
A. Hagiwara, S. Fujita, Y. Ohno, S. Aoki
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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