Results 71 to 80 of about 66,594 (293)

Methodological and terminological issues in animal-assisted interventions: An umbrella review of systematic reviews [PDF]

open access: yes, 2020
Recently, animal-assisted interventions (AAIs), which are defined as psychological, educational, and rehabilitation support activities, have become widespread in different contexts.
Amato, A.   +5 more
core   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort   +3 more
wiley   +1 more source

Terms of specialized nursing language for chronic renal patients undergoing conservative treatment [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to validate the terms of the specialized nursing language used in the care of people with chronic kidney disease undergoing conservative treatment identified in the literature by mapping them with terms of the International Classification for
Harlon França de Menezes   +6 more
doaj   +3 more sources

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon   +13 more
wiley   +1 more source

ICNP® terminology subset to infants in Primary Health Care [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to describe the development of an ICNP® terminology subset for Nursing Consultation to infants in Primary Health Care. Methods: a methodological study, described in five stages, carried out from May to September 2018 with 15 nurses who ...
Cheila Karei Siega   +3 more
doaj   +3 more sources

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

Automated Identification of Nursing Diagnoses and Interventions From Nursing Records Using a Retrieval-Augmented Large Language Model Approach: Quantitative Study

open access: yesJournal of Medical Internet Research
BackgroundElectronic health records (EHRs) have been widely adopted, but most nursing records remain in unstructured free-text format, which limits the secondary use of nursing data.
Minye Li   +7 more
doaj   +1 more source

Language Barriers in Health Care Settings: An Annotated Bibliography of Research Literature [PDF]

open access: yes, 2003
Provides an overview of resources related to the prevalence, role, and effects of language barriers and access in health ...
Adam Piotrowski   +4 more
core  

Long-term continuous monitoring of the preterm brain with diffuse optical tomography and electroencephalography: A technical note on cap manufacturing [PDF]

open access: yes, 2016
open12noDiffuse optical tomography (DOT) has recently proved useful for detecting whole-brain oxygenation changes in preterm and term newborns' brains.
Amodio, Piero   +11 more
core   +2 more sources

Pharmacokinetic‐pharmacodynamic modelling of risankizumab using chronic plaque psoriasis real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Risankizumab is a high‐cost biologic treatment for chronic plaque psoriasis, an immune‐mediated inflammatory disease presenting with painful red scaly skin lesions. Inter‐individual heterogeneity in treatment response may be better addressed with personalised rather than fixed dosing. We sought to develop a pharmacokinetic/pharmacodynamic (
Charlotte M. Thomas   +16 more
wiley   +1 more source

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